Sökresultat - "platelet aggregation"

Protective effects of combined eptifibatide and ticagrelor in patients with unstable angina undergoing percutaneous coronary intervention: a single-center experience.

Shi S; Department of Cardiovascular Medicine, First Affiliated Hospital of Soochow University, No.188 Shizi Road, Suzhou, 215006, Jiangsu, China., Ling Z; Department of Interal Medicine, Weiting Community Health Center of Suzhou Industrial Park, Suzhou, China., Gu S; Department of Nephrology, Kunshan Third Hospital, Suzhou, China., Jiang T; Department of Cardiovascular Medicine, First Affiliated Hospital of Soochow University, No.188 Shizi Road, Suzhou, 215006, Jiangsu, China., Ling L; Department of Cardiovascular Medicine, First Affiliated Hospital of Soochow University, No.188 Shizi Road, Suzhou, 215006, Jiangsu, China. joylinling@126.com.

Journal Article , 2025

Reliable Surface Modification of ePTFE Using a Photoreactive Hemocompatible Peptide to Promote Endothelial Affinity and Antiplatelet Efficacy.

Zhang W; National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.; Plastic Surgery Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100144, China., Fukazawa K; National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe Shim-machi, Suita, Osaka 564-8565, Japan., Mahara A; National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe Shim-machi, Suita, Osaka 564-8565, Japan., Le HT; National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe Shim-machi, Suita, Osaka 564-8565, Japan., Soni R; National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe Shim-machi, Suita, Osaka 564-8565, Japan., Yamaoka T; National Cerebral and Cardiovascular Center Research Institute, 6-1 Kishibe Shim-machi, Suita, Osaka 564-8565, Japan.; Department of Clinical Engineering, Faculty of Health Sciences, Komatsu University, He 14-1, Mukai-motoori-machi, Komatsu, Ishikawa 923-0961, Japan.

Journal Article , 2025

Antiplatelet-anticoagulant, APAC, a mimic of endogenous heparin, is an antithrombotic with von Willebrand factor-mediated characteristics.

Jouppila A; Clinical Research institute HUCH, Helsinki, Finland; Research Program Unit in Systems Oncology, Medical Faculty, University of Helsinki, Helsinki, Finland. Electronic address: Annukka.Jouppila@hus.fi., Nevola I; Research Program Unit in Systems Oncology, Medical Faculty, University of Helsinki, Helsinki, Finland., Lemponen M; HUS Diagnostic Center, Department of Clinical Chemistry and Hematology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Mattila T; Research Program Unit in Systems Oncology, Medical Faculty, University of Helsinki, Helsinki, Finland., Lassila R; Research Program Unit in Systems Oncology, Medical Faculty, University of Helsinki, Helsinki, Finland; Coagulation Disorders Unit, Departments of Hematology and Clinical Chemistry (HUSLAB Laboratory Services), Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland; Aplagon Ltd., Helsinki, Finland.

Journal Article , 2025

Metal-based complexes with antiplatelet properties: antagonists of the platelet-activating factor receptor (PAFR) and other aggregating agents.

Philippopoulos AI; Laboratory of Inorganic Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece. atphilip@chem.uoa.gr., Demopoulos CA; Laboratory of Biochemistry, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis Zografou 15771, Athens, Greece.

Journal Article; Review , 2025

Direct evaluation of antiplatelet therapy in coronary artery disease by comprehensive image-based profiling of circulating platelets.

Hirose K; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Kodera S; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Nishikawa M; Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan. msknishikawa-tky@umin.ac.jp., Sato M; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Zhou Y; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Zhang H; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Minatsuki S; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Ishida J; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Takeda N; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Wang H; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Kong C; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Deng Y; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Chen J; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Zhang C; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Akita J; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Ibayashi Y; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Yang R; Department of Chemistry, The University of Tokyo, Tokyo, Japan., Kanno H; Department of Chemistry, The University of Tokyo, Tokyo, Japan.; Department of Neurosurgical Engineering and Translational Neuroscience, Tohoku University Graduate School of Medicine, Miyagi, Japan., Nitta N; CYBO Inc, Tokyo, Japan., Sugimura T; CYBO Inc, Tokyo, Japan., Takeda N; Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan., Kurano M; Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan., Yatomi Y; Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.; International University of Health and Welfare Graduate School, Tokyo, Japan., Goda K; Department of Chemistry, The University of Tokyo, Tokyo, Japan. goda@chem.s.u-tokyo.ac.jp.; CYBO Inc, Tokyo, Japan. goda@chem.s.u-tokyo.ac.jp.; Department of Bioengineering, University of California, Los Angeles, CA, USA. goda@chem.s.u-tokyo.ac.jp.; Institute of Technological Sciences, Wuhan University, Hubei, China. goda@chem.s.u-tokyo.ac.jp.; International Center for Synchrotron Radiation Innovation Smart (SRIS), Tohoku University, Miyagi, Japan. goda@chem.s.u-tokyo.ac.jp.

Journal Article , 2025

Dendrobium nobile lindl extract modulates integrin αIIbβ3-mediated signaling pathways to inhibit platelet activation and thrombosis.

Hua C; Department of Pharmacology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, 561113, China., Wu M; Department of Pharmacology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, 561113, China., Xiao Y; Department of Pharmacology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, 561113, China., Zhang R; School of Pharmacy, Guizhou Medical University, Guiyang, 561113, China., Yuan Y; Department of Pharmacology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, 561113, China., Zhang L; School of Pharmacy, Guizhou Medical University, Guiyang, 561113, China., Guo F; Department of Pharmacology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, 561113, China., Liu J; School of Laboratory Animal & Shandong Laboratory Animal Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, 250117, China. Electronic address: ljian@sdfmu.edu.cn., Yang Z; School of Pharmacy, Guizhou Medical University, Guiyang, 561113, China. Electronic address: yangzhanzhan@gmc.edu.cn., Liu G; Department of Pharmacology, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, 561113, China; Guizhou Provincial Key Laboratory of Pathogenesis and Drug Research on Common Chronic Diseases, Guizhou Medical University, Guiyang, 561113, China; Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D, Guizhou Medical University, Guiyang, 561113, China. Electronic address: liug@gmc.edu.cn.

Journal Article , 2025

Antithrombotic effect and plasma pharmacochemistry of Justicia Procumbens L.

Zhang H; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, China., Liu Y; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China., Hu F; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, China., Chen S; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China., Xie Z; Hubei Provincial Hospital of Integrated Chinese & Western Medicine, Wuhan, China., Wu H; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, China.; Modern Engineering Research Center of Traditional Chinese Medicine and Ethnic Medicine of Hubei Province, Wuhan, China.; Hubei Shizhen Laboratory, Wuhan, China., Zhang T; Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China., Liu B; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, China.; Modern Engineering Research Center of Traditional Chinese Medicine and Ethnic Medicine of Hubei Province, Wuhan, China.; Hubei Shizhen Laboratory, Wuhan, China.

Journal Article , 2025

Exploring the quality marker of Curcumae kwangsiensis radix from different production regions using the spectrum-effect relationship, serum metabolism, and molecular docking integrated with chemometrics.

Yao Y; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China., Wang J; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China., Zhang G; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China., Li Z; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China., Yu H; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China., Zhao J; College of Pharmacy, Guangxi Medical University, Nanning, 530021, China., Huang M; College of Pharmacy, Fujian Key Laboratory of Chinese Materia Medica, Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, China., Yao C; Guangxi University of Chinese Medicine, Nanning, 530001, China., Wang Y; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China; College of Pharmacy, Fujian Key Laboratory of Chinese Materia Medica, Fujian University of Traditional Chinese Medicine, Fuzhou, 350108, China. Electronic address: ytwang@um.edu.mo., Luo H; Macau Centre for Research and Development in Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, China; College of Pharmacy, Guangxi Medical University, Nanning, 530021, China.

Journal Article , 2025

Genetically Proxied Antiplatelet Drug Target Perturbation and Risk of Aneurysmal Subarachnoid Hemorrhage: A Mendelian Randomization Analysis.

Fan YX; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China; China International Neuroscience Institute (China-INI), Xuanwu Hospital, Capital Medical University, Beijing, China., Yang CB; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China; China International Neuroscience Institute (China-INI), Xuanwu Hospital, Capital Medical University, Beijing, China., Song ZH; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China; China International Neuroscience Institute (China-INI), Xuanwu Hospital, Capital Medical University, Beijing, China., Yang X; Department of Neurosurgery, The First People's Hospital of Guiyang, Guiyang, China., Ma YJ; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China; China International Neuroscience Institute (China-INI), Xuanwu Hospital, Capital Medical University, Beijing, China., Zhang HQ; Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China; China International Neuroscience Institute (China-INI), Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address: xwzhanghq@163.com.

Journal Article , 2025

Effects of 3,5,4'-tri-[4-(nitrooxy)butanoyl]oxy resveratrol, a new nitric oxide-releasing derivative of resveratrol, on platelet activation.

Guglielmini G; Division of Internal and Cardiovascular Medicine, Department of Medicine and Surgery, University of Perugia, Strada Vicinale Via Delle Corse, 06132, Perugia, Italy., Berardi E; Division of Internal and Cardiovascular Medicine, Department of Medicine and Surgery, University of Perugia, Strada Vicinale Via Delle Corse, 06132, Perugia, Italy., Messina F; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Marcotullio MC; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Gresele P; Division of Internal and Cardiovascular Medicine, Department of Medicine and Surgery, University of Perugia, Strada Vicinale Via Delle Corse, 06132, Perugia, Italy. paolo.gresele@unipg.it.

Journal Article , 2025

Platelets and diseases: signal transduction and advances in targeted therapy.

Tian Y; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Microsurgery on Extremities, and Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zong Y; Centre for Orthopaedic Research, Medical School, The University of Western Australia, Nedlands, Western Australia, Australia., Pang Y; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Microsurgery on Extremities, and Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zheng Z; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Microsurgery on Extremities, and Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Ma Y; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Microsurgery on Extremities, and Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang C; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhangcq@sjtu.edu.cn.; Institute of Microsurgery on Extremities, and Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhangcq@sjtu.edu.cn., Gao J; Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. colingjj@163.com.; Institute of Microsurgery on Extremities, and Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. colingjj@163.com.

Journal Article; Review , 2025

A novel antibody against GPIbα inhibits platelet function and thrombosis without increasing bleeding.

Zhao L; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Du J; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Jin Y; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Hu Y; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Zhang S; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Yang B; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Sun C; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Zhao Y; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Ge X; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Yan R; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Liu C; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Hu R; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China., Dai K; Jiangsu Institute of Hematology, Cyrus Tang Medical Institute, The First Affiliated Hospital and Collaborative Innovation Center of Hematology, Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, National Clinical Research Center for Hematological Diseases, Suzhou, China.

Journal Article , 2025

Development of Zafirlukast Analogues for Improved Antithrombotic Activity Through Thiol Isomerase Inhibition.

Keovilay JA; Department of Pharmaceutical and Administrative Sciences, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (J.A.K., S.E.W., M.K.S., D.R.K.).; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, United Kingdom (J.A.K., K.A.T., S.K., T.S., J.M.G., D.R.K.)., Howard KC; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington (K.C.H., N.T.C., C.H., O.V.T., S.G.-T.)., Taylor KA; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, United Kingdom (J.A.K., K.A.T., S.K., T.S., J.M.G., D.R.K.)., Khan S; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, United Kingdom (J.A.K., K.A.T., S.K., T.S., J.M.G., D.R.K.)., Wurl SE; Department of Pharmaceutical and Administrative Sciences, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (J.A.K., S.E.W., M.K.S., D.R.K.)., Szahaj MK; Department of Pharmaceutical and Administrative Sciences, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (J.A.K., S.E.W., M.K.S., D.R.K.)., Sage T; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, United Kingdom (J.A.K., K.A.T., S.K., T.S., J.M.G., D.R.K.)., Chandrika NT; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington (K.C.H., N.T.C., C.H., O.V.T., S.G.-T.)., Hou C; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington (K.C.H., N.T.C., C.H., O.V.T., S.G.-T.)., Tsodikov OV; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington (K.C.H., N.T.C., C.H., O.V.T., S.G.-T.)., Gibbins JM; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, United Kingdom (J.A.K., K.A.T., S.K., T.S., J.M.G., D.R.K.)., Garneau-Tsodikova S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington (K.C.H., N.T.C., C.H., O.V.T., S.G.-T.)., Kennedy DR; Department of Pharmaceutical and Administrative Sciences, College of Pharmacy and Health Sciences, Western New England University, Springfield, MA (J.A.K., S.E.W., M.K.S., D.R.K.).; Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, United Kingdom (J.A.K., K.A.T., S.K., T.S., J.M.G., D.R.K.).; Department of Medicine, UMass Chan Medical School-Baystate Campus, Springfield (D.R.K.).

Journal Article; Comparative Study , 2025

The Effects of Aspirin dose in Children with Congenital and Acquired Heart Disease. Results from the Paediatric Study of Aspirin Efficacy using Diagnostic and Monitoring Tools (PAED-M).

Regan IE; Department of Coagulation/Haematology, Children's Health Ireland at Crumlin, Dublin, Ireland.; School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland.; National Children's Research Centre, Children's Health Ireland, Dublin, Ireland., Cox D; School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons Ireland, Dublin, Ireland., Kelleher ST; Department of Paediatric Cardiology, Children's Health Ireland at Crumlin, Dublin, Ireland., McMahon CJ; Department of Paediatric Cardiology, Children's Health Ireland at Crumlin, Dublin, Ireland. cmcmahon992004@yahoo.com.; School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland. cmcmahon992004@yahoo.com.; School of Health Professions Education (SHE), Maastricht University, Maastricht, Netherlands. cmcmahon992004@yahoo.com.; National Children's Research Centre, Children's Health Ireland, Dublin, Ireland. cmcmahon992004@yahoo.com.

Journal Article; Observational Study , 2025

The soluble guanylate cyclase (sGC) stimulator vericiguat inhibits platelet activation and thrombosis.

Zhou W; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Zhou L; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Qi Z; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Dai S; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Zhang P; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Zhong H; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Xu H; Department of Infectious Disease, Zhongshan Hospital, Fudan University, Shanghai, China., Zhao X; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Lian X; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China., Lin J; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China. Electronic address: lin.jiaxiong@zs-hospital.sh.cn., Wu H; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China; National Clinical Research Center for Interventional Medicine, China. Electronic address: wu.hongyi@zs-hospital.sh.cn.

Journal Article , 2025

Design, synthesis, and biological evaluation of Pamicogrel derivatives as potential antiplatelet agents.

Yuan L; Jilin Provincial Institute of Pharmaceutical Research, Changchun 130061, People's Republic of China. Electronic address: 124177261@qq.com., Chu QR; Jilin Provincial Institute of Pharmaceutical Research, Changchun 130061, People's Republic of China., Li FX; Jilin Provincial Institute of Pharmaceutical Research, Changchun 130061, People's Republic of China., Zhang DK; Jilin Provincial Institute of Pharmaceutical Research, Changchun 130061, People's Republic of China., Yu YX; Jilin Provincial Institute of Pharmaceutical Research, Changchun 130061, People's Republic of China., Liu JC; Jilin Provincial Institute of Pharmaceutical Research, Changchun 130061, People's Republic of China.

Journal Article , 2025

Predictive Value of Platelet Aggregation Tests in Recurrent Cerebral Ischemia and Major Bleeding.

Ishiguro M; Department of Systems Neuroscience, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido, Japan., Kurokawa Y; Division of Physiology, Seisa Dohto University, Kitahiroshima, Hokkaido, Japan., Tanooka A; Division of Neurosurgery, Asahikawa Neurosurgical Hospital, Asahikawa, Hokkaido, Japan., Nagamine T; Department of Systems Neuroscience, School of Medicine, Sapporo Medical University, Sapporo, Hokkaido, Japan.

Journal Article , 2025

Fucosylated Glycosaminoglycan Oligosaccharide HS14, Derived from Sea Cucumbers, Is a Novel Inhibitor of Platelet Toll-like Receptor 2.

Sun H; School of Chemistry and Materials Science, South-Central Minzu University, Wuhan 430074, China., Zhu G; College of Life Sciences, South-Central Minzu University, Wuhan 430074, China., Li S; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China., Li P; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China., Zhang J; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China., Yin R; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China., Yuan L; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China., Gao N; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China., Zhao J; School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan 430074, China.

Journal Article , 2025

Association of P2RY12 Gene Variants and Non-Genetic Factors With Clopidogrel Responsiveness in Vietnamese Patients After Percutaneous Coronary Intervention: A Cross-Sectional Study.

Ta Anh H; Cardiovascular Center, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.; Cardiovascular Intervention Department, 175 Military Hospital, Ho Chi Minh City, Vietnam., Nguyen Duy T; Cardiovascular Center, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam., Bui Duc T; Cardiovascular Intervention Department, 175 Military Hospital, Ho Chi Minh City, Vietnam., Hoang Van T; Institute of Biomedicine and Pharmacy, Vietnam Military Medical University, Hanoi, Vietnam., Nguyen Oanh O; Cardiovascular Center, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam., Luong Cong T; Cardiovascular Center, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam., Truong Dinh C; Cardiovascular Intervention Department, 175 Military Hospital, Ho Chi Minh City, Vietnam.

Journal Article , 2025

UNC9426, a Potent and Orally Bioavailable TYRO3-Specific Inhibitor.

Kong D; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Yang X; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Judd S; Versiti Blood Research Institute, Wauwatosa, Wisconsin 53226, United States., Yan D; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia 30322, United States., Springborn S; Versiti Blood Research Institute, Wauwatosa, Wisconsin 53226, United States., Stashko MA; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Kidwell A; Versiti Blood Research Institute, Wauwatosa, Wisconsin 53226, United States., Huelse JM; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia 30322, United States., Kireev D; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States., Graham DK; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia 30322, United States., DeRyckere D; Aflac Cancer and Blood Disorders Center of Children's Healthcare of Atlanta and Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia 30322, United States., Branchford B; Versiti Blood Research Institute, Wauwatosa, Wisconsin 53226, United States., Wang X; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.; Lineberger Comprehensive Cancer Center, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

Journal Article , 2025