Sökresultat - "triggering receptor expressed on myeloid cells-1"

JNK kinase promotes inflammatory responses by inducing the expression of the inflammatory amplifier TREM1 during influenza a virus infection.

Chen N; MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China. Electronic address: chennafz@qq.com., Jin J; MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China. Electronic address: jinjyjo@qq.com., Qiao B; MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China., Gao Z; MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China., Tian Y; MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China. Electronic address: 326844254@qq.com., Ping J; MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China. Electronic address: jihui.ping@njau.edu.cn.

Journal Article , 2025

Endothelial TREM-1 mediates sepsis-induced blood‒brain barrier disruption and cognitive impairment via the PI3K/Akt pathway.

Su Y; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China., Zhu W; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China., Su T; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China., Huang L; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China., Qin M; Emergency Department, The State Key Laboratory of Complex, Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China., Wang Q; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China., Xu Q; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China. xuqi@pumc.edu.cn.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China. xuqi@pumc.edu.cn., Li Y; Emergency Department, The State Key Laboratory of Complex, Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China. billliyi@126.com., Xiu J; State Key Laboratory of Common Mechanism Research for Major Diseases, Institute of Basic Medical Sciences, School of Basic Medicine Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 100005, China. xiujianbo@ibms.cams.cn.; Neuroscience Center, Chinese Academy of Medical Sciences, Beijing, 100005, China. xiujianbo@ibms.cams.cn.; State Key Laboratory of Complex, Severe, and Rare Diseases, Beijing, 100005, China. xiujianbo@ibms.cams.cn.

Journal Article , 2025

Activated TREM1-mediated MAPK signaling in endothelial cells caused by highly expressed STAT1 is associated with intracranial aneurysms occurrence and rupture.

Zhu H; Cheeloo College of Medicine, Shandong University, No.44 Wenhua West Road, Lixia District, Jinan, 250012, China.; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No.1 Swan Lake Road, Hefei, 230001, China., Gao G; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No.1 Swan Lake Road, Hefei, 230001, China., Wu Y; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No.1 Swan Lake Road, Hefei, 230001, China., Wang Y; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No.1 Swan Lake Road, Hefei, 230001, China., Chen Y; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No.1 Swan Lake Road, Hefei, 230001, China., Niu C; Cheeloo College of Medicine, Shandong University, No.44 Wenhua West Road, Lixia District, Jinan, 250012, China. niuchaoshi@126.com.; Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No.1 Swan Lake Road, Hefei, 230001, China. niuchaoshi@126.com.

Journal Article , 2025

Uncovering the role of TREM-1 in celiac disease: In silico insights into the recognition of gluten-derived peptides and inflammatory mechanisms.

de Oliveira Matos A; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil. Electronic address: amandamatos@discente.ufg.br., Henrique Dos Santos Dantas P; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil. Electronic address: pedrohenrique1997@discente.ufg.br., Rodrigues do Carmo Neto J; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil. Electronic address: zerodrigues@ufg.br., Contreras Colmenares MT; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil. Electronic address: mkcntrrs@gmail.com., Felice AG; Institute of Biological and Natural Sciences, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil. Electronic address: andreigf@hotmail.com., de Castro Soares S; Institute of Biological and Natural Sciences, Federal University of Triângulo Mineiro, Uberaba, Minas Gerais, Brazil. Electronic address: siomars@gmail.com., Silva-Sales M; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil. Electronic address: marcellesales@ufg.br., Sales-Campos H; Institute of Tropical Pathology and Public Health, Federal University of Goiás, Goiânia, Brazil. Electronic address: tonsales@ufg.br.

Journal Article , 2025

Shortened PGLYRP1 Peptides Regulate Antitumor Activity of Cytotoxic Lymphocytes via TREM-1 Receptor: From Biology to Bioinformatics.

Yurkina DM; Institute of Gene Biology (RAS), 119334 Moscow, Russia., Shcherbakov KA; Institute of Gene Biology (RAS), 119334 Moscow, Russia., Romanova EA; Institute of Gene Biology (RAS), 119334 Moscow, Russia., Tvorogova AV; Institute of Gene Biology (RAS), 119334 Moscow, Russia., Feoktistov AM; Institute of Gene Biology (RAS), 119334 Moscow, Russia.; Institute of Molecular Biology (RAS), 119334 Moscow, Russia., Georgiev GP; Institute of Gene Biology (RAS), 119334 Moscow, Russia., Yashin DV; Institute of Gene Biology (RAS), 119334 Moscow, Russia., Sashchenko LP; Institute of Gene Biology (RAS), 119334 Moscow, Russia.

Journal Article , 2025

TREM-1-Linked Inflammatory Cargo in SARS-CoV-2-Stimulated Macrophage Extracellular Vesicles Drives Cellular Senescence and Impairs Antibacterial Defense.

da Silva-Neto PV; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil.; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-FCFRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil., de Carvalho JCS; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil.; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-FCFRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil., Toro DM; Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14049-900, SP, Brazil., Oliveira BTM; Departamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14049-900, SP, Brazil., Cominal JG; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil., Castro RC; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-FCFRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil., Almeida MA; Departamento de Medicina Veterinária, Faculdade de Zootecnia e Engenharia de Alimentos-FZEA, Universidade de São Paulo-USP, Pirassununga 13635-900, SP, Brazil., Prado CM; Departamento de Medicina Veterinária, Faculdade de Zootecnia e Engenharia de Alimentos-FZEA, Universidade de São Paulo-USP, Pirassununga 13635-900, SP, Brazil., Arruda E; Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14049-900, SP, Brazil., Frantz FG; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-FCFRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil., Ramos AP; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil., Ciancaglini P; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil.; Departamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14049-900, SP, Brazil., Martins RB; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-FCFRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil., da Silveira JC; Departamento de Medicina Veterinária, Faculdade de Zootecnia e Engenharia de Alimentos-FZEA, Universidade de São Paulo-USP, Pirassununga 13635-900, SP, Brazil., Almeida F; Departamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14049-900, SP, Brazil., Malmegrim KCR; Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto-FCFRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil., Sorgi CA; Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil.; Departamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14049-900, SP, Brazil.; Programa de Pós-graduação em Imunologia Básica e Aplicada-PPGIBA, Instituto de Ciências Biológicas, Universidade Federal do Amazonas-UFAM, Manaus 69080-900, AM, Brazil.

Journal Article , 2025

Blocking triggering receptors expressed on myeloid cell-1 alleviates alveolar epithelial cell senescence by inhibiting oxidative stress in pulmonary fibrosis.

Zhong WJ; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Xiong JB; Department of Emergency, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China.; National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China., Zhang CY; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Jin L; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Yang NS; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Sha HX; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Liu YB; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Duan JX; Department of Geriatrics, Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China.; National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China., Guan CX; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Zhou Y; Department of Physiology, School of Basic Medical Science, Central South University, Changsha, 410078, Hunan, China., Su F; Department of Emergency, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China. sufeng@csu.edu.cn.; National Clinical Research Center of Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, 410078, Hunan, China. sufeng@csu.edu.cn.

Journal Article , 2025

N6-methyladenosine-mediated overexpression of TREM-1 is associated with periodontal disease.

Burra Anand D; Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India., Ramamurthy J; Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India., Kannan B; Molecular Biology Lab, Centre for Cellular and Molecular Research, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 600077, India., Jayaseelan VP; Clinical Genetics Lab, Centre for Cellular and Molecular Research, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India., Arumugam P; Molecular Biology Lab, Centre for Cellular and Molecular Research, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, 600077, India. paramasivama.sdc@saveetha.com.

Journal Article , 2025

HBCOC attenuates cerebral ischemia-reperfusion injury in mice by inhibiting the inflammatory response and autophagy via TREM-1/ERK/NF-κB.

Li R; Department of Anesthesiology, The General Hospital of Western Theater Command, Sichuan, Chengdu, China., Li Q; Department of Anesthesiology, Xindu District People's Hospital of Chengdu, Sichuan, Chengdu, China., Yang C; Department of Anesthesiology, The General Hospital of Western Theater Command, Sichuan, Chengdu, China., Liu H; Department of Anesthesiology, The Affiliated Chengdu 363 hospital of Southwest Medical University, Sichuan, Chengdu, China., Xiao Y; Department of Anesthesiology, The General Hospital of Western Theater Command, Sichuan, Chengdu, China., Yang P; Department of Anesthesiology, Chengdu Medical College, Sichuan, Chengdu, China., Gong G; Department of Anesthesiology, The General Hospital of Western Theater Command, Sichuan, Chengdu, China., Wu W; Department of Anesthesiology, The General Hospital of Western Theater Command, Sichuan, Chengdu, China. Electronic address: wuweizj@163.com.

Journal Article , 2025

Soluble Triggering Receptors on Myeloid Cells-1 Could Be a Potential Biomarker for Disease Activity in Familial Mediterranean Fever.

Cemiloglu M; Department of Molecular Biochemistry and Genetics, Health Science Institute, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey., Ozcan O; Department of Biochemistry, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey., Kimyon G; Department of Rheumatology, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey., Arpaci A; Department of Biochemistry, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey., Oguzman H; Department of Biochemistry, Faculty of Medicine, Hatay Mustafa Kemal University, Antakya, Hatay, Turkey.

Journal Article , 2025

Diagnostic value of sTREM-1, sCD25, sCD40L and sCD130 in late-onset neonatal sepsis.

Duan Y; Department of Laboratory, The First People's Hospital of Bengbu, Bengbu, 233000, China. Electronic address: 758665563@qq.com., Li P; Kunming Medical University, Kunming, 650500, China., Liang Y; Department of Laboratory, The First People's Hospital of Bengbu, Bengbu, 233000, China., Chen Y; Department of Laboratory, The First People's Hospital of Bengbu, Bengbu, 233000, China.

Journal Article; Letter , 2025

Gut-derived macrophages link intestinal damage to brain injury after cardiac arrest through TREM1 signaling.

Chang Y; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Chen J; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Peng Y; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhang K; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhang Y; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Zhao X; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Wang D; Dermatology Hospital, Southern Medical University, Guangzhou, China., Li L; Clinical Laboratory, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China., Zhu J; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Liu K; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Li Z; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China., Pan S; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China. pansuyue@smu.edu.cn., Huang K; Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China. hkb@smu.edu.cn.; Department of Neurology, Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou, China. hkb@smu.edu.cn.

Journal Article , 2025

[ ⁶⁸ Ga]Ga-NOTA-C-IPB-AIT: A novel radiotracer for in vivo detection of TREM-1 expression.

Pan Y; Key Laboratory for Experimental Teratology of the Ministry of Education and Research Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China., Zhang X; Key Laboratory for Experimental Teratology of the Ministry of Education and Research Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China; Department of Radiation Oncology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China., Diao C; Key Laboratory for Experimental Teratology of the Ministry of Education and Research Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China., Zhang J; Key Laboratory for Experimental Teratology of the Ministry of Education and Research Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China., Lin Y; Key Laboratory for Experimental Teratology of the Ministry of Education and Research Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China., Sun X; Department of Radiology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China. Electronic address: rgsuper@163.com., Li M; Department of Nuclear Medicine, 960th Hospital of PLA, Jinan, Shandong, China. Electronic address: liminyingxiang@163.com., Gao F; Key Laboratory for Experimental Teratology of the Ministry of Education and Research Center for Experimental Nuclear Medicine, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China. Electronic address: rggaofeng@sdu.edu.cn.

Journal Article , 2025

Co-Expression of Dominant-Negative TGF-β Receptor 2 Enhances the Therapeutic Efficacy of Novel TREM1/DAP12-BB-Based CAR-T Cells in Solid Tumours.

Zhu S; Nanjing CART Medical Technology Co. Ltd., Nanjing, P.R. China., Hu J; Nanjing CART Medical Technology Co. Ltd., Nanjing, P.R. China., Lin J; Department of Pathology, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, P.R. China., Wang C; Nanjing CART Medical Technology Co. Ltd., Nanjing, P.R. China., Wang E; Nanjing CART Medical Technology Co. Ltd., Nanjing, P.R. China.; Department of Pathology, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, P.R. China.; Clinical Pathological Diagnosis & Research Center, Youjiang Medical University for Nationalities, Baise, P.R. China.; The Key Laboratory of Molecular Pathology (Hepatobiliary Diseases) of Guangxi, Baise, P.R. China.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Soluble epoxide hydrolase inhibition impairs triggering receptor expressed on myeloid cells-1 in periodontal tissue.

Vargas BDS; Laboratory of Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Campinas, Brazil., Vargas BSF; Laboratory of Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Campinas, Brazil., Clemente-Napimoga JT; Laboratory of Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Campinas, Brazil., Hammock BD; Department of Entomology and UCD Comprehensive Cancer Center, University of California, Davis, California, USA., Abdalla HB; Laboratory of Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Campinas, Brazil., Van Dyke TE; Department of Immunology and Inflammation, The ADA Forsyth Institute, Cambridge, Massachusetts, USA.; Department of Oral Medicine, Infection, and Immunity, Faculty of Medicine, Harvard University, Boston, Massachusetts, USA., Napimoga MH; Laboratory of Neuroimmune Interface of Pain Research, Faculdade São Leopoldo Mandic, Instituto de Pesquisa São Leopoldo Mandic, Campinas, Brazil.

Journal Article , 2025

The properties of TREM1 and its emerging role in pain-related diseases.

Fan Z; Department of Neurology, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, 730000, China., Wang L; Expert Workstation of Academician Wang Longde, Lanzhou University Second Hospital, Lanzhou, 730000, China., Sun S; Department of Neurology, Henan Provincial People's Hospital, Zhengzhou, 450003, China. sstlucky@163.com., Ge Z; Department of Neurology, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, 730000, China. GZMcourage1136@163.com.; Expert Workstation of Academician Wang Longde, Lanzhou University Second Hospital, Lanzhou, 730000, China. GZMcourage1136@163.com.; Gansu Provincial Neurology Clinical Medical Research Center, Lanzhou University Second Hospital, Lanzhou, 730000, China. GZMcourage1136@163.com.

Journal Article; Review , 2025

TREM1 interferes with macrophage mitophagy via the E2F1-mediated TOMM40 transcription axis in rheumatoid arthritis.

Dai ZZ; Department of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Institute for Pediatric Research, Shanghai, China., Xu J; Department of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhang Q; Department of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Zhou H; Department of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China., Liu XM; Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China; Shanghai Institute for Pediatric Research, Shanghai, China. Electronic address: 22910325@sjtu.edu.cn., Li H; Department of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address: lihai@xinhuamed.com.cn.

Journal Article , 2025

Infiltrating peripheral monocyte TREM-1 mediates dopaminergic neuron injury in substantia nigra of Parkinson's disease model mice.

Song W; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China.; Yancheng Stomatological Hospital, Yancheng, China., Zhou ZM; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China., Zhang LL; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China., Shu HF; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China., Xia JR; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China., Qin X; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China., Hua R; Department of Emergency, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. ilovezq@yeah.net., Zhang YM; NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, China. zhangym700@163.com.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China. zhangym700@163.com.; Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, China. zhangym700@163.com.

Journal Article , 2025

Tissue-resident CCR2 ⁺ macrophage TREM-1/3 signaling is necessary for monocyte and neutrophil recruitment to injured hearts.

Terada Y; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Li W; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Amrute JM; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Bery AI; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Liu CR; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Nunna V; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Frye CC; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Dun H; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Koenig AL; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Luehmann HP; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Heo GS; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Owen MC; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Wein AN; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Liu Y; Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Ritter JH; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Prabhu SD; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Nava RG; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Gelman AE; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Cella M; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Colonna M; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Lavine KJ; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: klavine@wustl.edu., Kreisel D; Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: kreiseld@wustl.edu.

Journal Article , 2025

Surface triggering receptor expressed on myeloid cells-1 (sTREM1) in critically ill children: a prospective observational controlled study.

Rashad Fouda E; Department of Pediatrics, Faculty of Medicine, Menoufia University, Menoufia, Egypt., Abd Elghany SH; Department of Pediatrics, Faculty of Medicine, Menoufia University, Menoufia, Egypt., Ahmed Omar T; Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Menoufia, Egypt., Abdelaziz AA; Department of Pediatrics, Faculty of Medicine, Menoufia University, Menoufia, Egypt.

Journal Article; Observational Study , 2025