Sökresultat - "virus replication"

The rabies virus matrix protein (RABV M) interacts with host histone deacetylase 6 (HDAC6) to activate the MEK/ ERK signaling pathway and enhance viral replication.

Yin J; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China; College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China., Wang S; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China., Zhang Z; College of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730070, China., Ge J; College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang, China., Zhang Q; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China., Sun Y; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China., Yin X; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China. Electronic address: yinxiangping@caas.cn., Wang X; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China. Electronic address: wangxiangwei@caas.cn.

Journal Article , 2025

Rev-RRE activity modulates HIV-1 replication and latency reactivation: Implications for viral persistence and cure strategies.

Dzhivhuho GA; Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America.; Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America., Jackson PEH; Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America.; Division of Infectious Diseases and International Health, Department of Medicine, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America., Honeycutt ES; Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America.; Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America., Mesquita FDS; Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America., Huang J; Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America., Hammarskjold ML; Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America.; Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America., Rekosh D; Department of Microbiology, Immunology, and Cancer Biology, School of Medicine, University of Virginia, Charlottesville, Virginia, United States of America.; Myles H. Thaler Center for HIV and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America.

Journal Article , 2025

Interferon and TLR genes, but not endogenous bornavirus-like elements, limit BoDV1 replication after intracerebral infection.

Koide R; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research and RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Abe T; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan., Harimoto T; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research and RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Kamada AJ; Department of Biology, University of Oxford, Oxford, United Kingdom., Saito Y; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research and RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Guerrini M; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Fujii A; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research and RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Parrish E; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research and RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Horie M; Graduate School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.; Osaka International Research Center for Infectious Diseases, Osaka Metropolitan University, Osaka, Japan., Kiyonari H; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan., Yamamoto K; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Tomonaga K; Laboratory of RNA Viruses, Department of Virus Research, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.; Laboratory of RNA Viruses, Department of Mammalian Regulatory Network, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.; Department of Molecular Virology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Parrish NF; Genome Immunobiology RIKEN Hakubi Research Team, RIKEN Cluster for Pioneering Research and RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

Journal Article , 2025

Trehalose supports the growth of Aedes aegypti cells and modifies gene expression and dengue virus type 2 replication.

Marten AD; Foundational Sciences, Central Michigan University College of Medicine, Mount Pleasant, Michigan, United States of America., Haslitt DP; Foundational Sciences, Central Michigan University College of Medicine, Mount Pleasant, Michigan, United States of America., Martin CA; Foundational Sciences, Central Michigan University College of Medicine, Mount Pleasant, Michigan, United States of America., Karthikeyan A; Foundational Sciences, Central Michigan University College of Medicine, Mount Pleasant, Michigan, United States of America., Swanson DH; Department of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan, United States of America., Kalera K; Department of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan, United States of America.; Biochemistry, Cell, and Molecular Biology Graduate Programs, Central Michigan University, Mount Pleasant, Michigan, United States of America., Johnson UG; Department of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan, United States of America.; Biochemistry, Cell, and Molecular Biology Graduate Programs, Central Michigan University, Mount Pleasant, Michigan, United States of America., Swarts BM; Department of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan, United States of America.; Biochemistry, Cell, and Molecular Biology Graduate Programs, Central Michigan University, Mount Pleasant, Michigan, United States of America., Conway MJ; Foundational Sciences, Central Michigan University College of Medicine, Mount Pleasant, Michigan, United States of America.

Journal Article , 2025

HBV shows different levels of adaptation to HLA class I-associated selection pressure correlating with markers of replication.

Schwarz T; Institute of Virology, University of Düsseldorf, Faculty of Medicine, Düsseldorf, Germany; Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Ptok J; Institute of Virology, University of Düsseldorf, Faculty of Medicine, Düsseldorf, Germany., Damagnez M; Institute of Virology, University of Düsseldorf, Faculty of Medicine, Düsseldorf, Germany., Menne C; Institute of Virology, University of Düsseldorf, Faculty of Medicine, Düsseldorf, Germany., Alizei ES; Clinic for Internal Medicine II, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Lang-Meli J; Clinic for Internal Medicine II, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Maas M; Clinic for Internal Medicine II, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Habermann D; Bioinformatics and Computational Biophysics, Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany., Hoffmann D; Bioinformatics and Computational Biophysics, Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany., Schulze Zur Wiesch J; Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lauer GM; Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts, USA., Kefalakes H; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Cornberg M; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Kraft ARM; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Gliga S; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Bock HH; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Horn PA; Institute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Maini MK; Division of Infection and Immunity, Institute of Immunity and Transplantation, University College London, London, United Kingdom., Thimme R; Clinic for Internal Medicine II, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany., Wedemeyer H; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany., Nattermann J; Department of Internal Medicine I, University Hospital of Bonn, Bonn, Germany., Heinemann FM; Institute for Transfusion Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Luedde T; Department of Gastroenterology, Hepatology and Infectious Diseases, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany., Neumann-Haefelin C; Clinic for Internal Medicine II, Freiburg University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany; Department of Gastroenterology and Hepatology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Walker A; Institute of Virology, University of Düsseldorf, Faculty of Medicine, Düsseldorf, Germany., Timm J; Institute of Virology, University of Düsseldorf, Faculty of Medicine, Düsseldorf, Germany. Electronic address: joerg.timm@uni-duesseldorf.de.

Journal Article , 2025

Darunavir inhibits dengue virus replication by targeting the hydrophobic pocket of the envelope protein.

Kan JY; The Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung, Taiwan; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan., Chang YJ; The Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung, Taiwan., Lai HC; Division of Hepato-Gastroenterology, Department of Internal Medicine, China Medical University Hospital, Taichung 404332, Taiwan., Lin HH; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan., Chiu SW; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu City, Taiwan., Hung PY; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan., Lu CH; Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu City, Taiwan. Electronic address: chlu@nycu.edu.tw., Lin CW; The Ph.D. Program of Biotechnology and Biomedical Industry, China Medical University, Taichung, Taiwan; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan; Department of Medical Laboratory Science and Biotechnology, Asia University, Taichung, Taiwan. Electronic address: cwlin@mail.cmu.edu.tw.

Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't , 2025

Nuclear AGO2 supports influenza A virus replication through type-I interferon regulation.

Huang HC; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Fong M; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Nowak I; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Shcherbinina E; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Lobo V; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Besavilla DF; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Huynh HT; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Schön K; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Westholm JO; Department of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Stockholm University, Box 1031, SE-17121 Solna, Sweden., Fernandez C; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Patel AAH; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, SE-40530 Gothenburg, Sweden., Wiel C; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, SE-40530 Gothenburg, Sweden., Sayin VI; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Center for Cancer Research, University of Gothenburg, SE-40530 Gothenburg, Sweden., Anastasakis DG; Department of Basic Sciences, School of Medicine, University of Crete, GR 70013 Heraklion ,Greece., Angeletti D; Department of Microbiology and Immunology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; SciLifeLab, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden., Sarshad AA; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, SE-40530 Gothenburg, Sweden.

Journal Article , 2025

The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle.

Faizo AAA; MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland., Bellward C; MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland., Hernandez-Lopez HR; MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland., Stevenson A; MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland., Gu Q; MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland., Graham SV; MRC-University of Glasgow Centre for Virus Research, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland.

Journal Article , 2025

High-resolution structure reveals enhanced 14-3-3 binding by a mutant SARS-CoV-2 nucleoprotein variant with improved replicative fitness.

Perfilova KV; A.N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia., Matyuta IO; A.N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia; Moscow Center for Advanced Studies, Kulakova Str. 20, 123592, Moscow, Russia., Minyaev ME; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia., Boyko KM; A.N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia., Cooley RB; GCE4All Center, Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR, 97331, USA., Sluchanko NN; A.N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia. Electronic address: nikolai.sluchanko@mail.ru.

Journal Article; Research Support, Non-U.S. Gov't , 2025

Visualizing the transcription and replication of influenza A viral RNAs in cells by multiple direct RNA padlock probing and in situ sequencing (mudRapp-seq).

Ahmad S; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080 Würzburg, Germany., Li J; Architecture et Réactivitié de l'ARN, Université de Strasbourg, CNRS, Institute of Molecular and Cellular Biology (IBMC), 2 Allée Konrad Roentgen, 67000 Strasbourg, France., Schaust J; Center for Computational and Theoretical Biology (CCTB), Faculty of Biology, Julius-Maximilians University of Würzburg, Am Hubland, 97074 Würzburg, Germany., Gribling-Burrer AS; Architecture et Réactivitié de l'ARN, Université de Strasbourg, CNRS, Institute of Molecular and Cellular Biology (IBMC), 2 Allée Konrad Roentgen, 67000 Strasbourg, France., Geiger N; Institute for Virology and Immunobiology, University of Würzburg, Versbacher Strasse 7, 97078 Würzburg, Germany., Fischer SC; Center for Computational and Theoretical Biology (CCTB), Faculty of Biology, Julius-Maximilians University of Würzburg, Am Hubland, 97074 Würzburg, Germany., Ambi UB; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080 Würzburg, Germany., Backes S; Institute for Virology and Immunobiology, University of Würzburg, Versbacher Strasse 7, 97078 Würzburg, Germany., Ankenbrand MJ; Center for Computational and Theoretical Biology (CCTB), Faculty of Biology, Julius-Maximilians University of Würzburg, Am Hubland, 97074 Würzburg, Germany., Smyth RP; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080 Würzburg, Germany.; Architecture et Réactivitié de l'ARN, Université de Strasbourg, CNRS, Institute of Molecular and Cellular Biology (IBMC), 2 Allée Konrad Roentgen, 67000 Strasbourg, France.

Journal Article , 2025

IFN-γ signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice.

Kerr CM; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America., Proctor-Roser MA; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America., Parthasarathy S; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America., O'Connor JJ; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America., Pfannenstiel JJ; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America., Orozco RC; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America., Fehr AR; Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America.

Journal Article , 2025

Bisbenzylisoquinoline alkaloids inhibit influenza virus replication by disrupting endosomal acidification.

Li B; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Qiao L; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Li X; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Yang G; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Wang K; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Wang H; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Wu S; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Yan H; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. yan0495@163.com., Jiang J; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Li Y; CAMS Key Laboratory of Antiviral Drug Research, Beijing Key Laboratory of Technology and Application for Anti-Infective New Drugs Research and Development, NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. yuhuanlibj@126.com.; State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. yuhuanlibj@126.com.

Journal Article , 2025

A detailed kinetic model of Eastern equine encephalitis virus replication in a susceptible host cell.

Larkin CI; Joint Carnegie Mellon University - University of Pittsburgh PhD Program in Computational Biology, Pittsburgh, Pennsylvania, United States of America.; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Dunn MD; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Shoemaker JE; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Klimstra WB; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Faeder JR; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

Journal Article , 2025

Luteolin-7-O-glucoside from Elsholtzia ciliata extract inhibits the replication of coronavirus.

Lee S; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea., Kim JH; Department of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Eumsung, Republic of Korea., Kim C; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea., Jung W; R&D team, Korea Mine Rehabilitation and Mineral Resources Corporation, Wonju, Korea., Park J; R&D team, Korea Mine Rehabilitation and Mineral Resources Corporation, Wonju, Korea., Park J; Division of Biological Science and Technology, Yonsei University, Wonju, Republic of Korea.

Journal Article , 2025

Multiple antiviral mechanisms of Ephedrae Herba and Cinnamomi Cortex against influenza: inhibition of entry and replication.

Fujikane A; Department of General Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka Prefecture, Japan., Fujikane R; Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Fukuoka, Fukuoka Prefecture, Japan.; Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Fukuoka Prefecture, Japan., Sechi Y; Department of General Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka Prefecture, Japan., Nishi A; TSUMURA Advanced Technology Research Laboratories, TSUMURA & CO., Inashiki-gun, Ibaraki Prefecture, Japan., Ishino Y; Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University, Fukuoka, Fukuoka Prefecture, Japan., Hiyoshi T; Department of General Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka Prefecture, Japan., Sakamoto A; Department of General Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka Prefecture, Japan., Nabeshima S; Department of General Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka Prefecture, Japan.

Journal Article , 2025

Novel strand-specific qPCR assay elucidates differences in viral replication kinetics between different strains of avian reovirus.

Harrell TL; US Department of Agriculture, Agricultural Research Service, US National Poultry Research Center, Athens, Georgia, USA., Alvarez-Narvaez S; US Department of Agriculture, Agricultural Research Service, US National Poultry Research Center, Athens, Georgia, USA., Read QD; US Department of Agriculture, Agricultural Research Service, Raleigh, North Carolina, USA., Conrad SJ; US Department of Agriculture, Agricultural Research Service, US National Poultry Research Center, Athens, Georgia, USA.

Journal Article , 2025

De novo design mini-binder proteins targeting the glycoproteins D to inhibit PRV replication in PK15 cells.

Wei L; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China; Hubei Jiangxia Laboratory, Wuhan, Hubei, PR China., Hu Y; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China., Liu Y; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China., Xing B; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China., Wang K; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China., Weng J; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China; Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, PR China., Liu Z; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China., Fang Y; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China., Ming K; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China; Hubei Jiangxia Laboratory, Wuhan, Hubei, PR China., Mei M; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China; Hubei Jiangxia Laboratory, Wuhan, Hubei, PR China., Wei Z; State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China; Hubei Jiangxia Laboratory, Wuhan, Hubei, PR China; Hubei Province Key Laboratory of Biotechnology of Chinese Traditional Medicine, National & Local Joint Engineering Research Center of High-throughput Drug Screening Technology, School of Life Sciences, Hubei University, Wuhan, Hubei, PR China. Electronic address: weizigong@163.com.

Journal Article , 2025

PRRSV Nsp4 induces ATGL protein degradation to promote viral replication and lipid droplet accumulation.

Xie E; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Wang Q; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Yi H; Key Laboratory of Animal Pathogen Infection and Immunology of Fujian Province, College of Animal Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, China., Wang J; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Liu X; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Ye R; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Lu L; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Tian T; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Chen A; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Zheng G; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China., Zhang G; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China; National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China., Wang H; Guangdong Provincial Key Laboratory of Zoonosis Prevention and Control, College of Veterinary Medicine, South China Agricultural University, Guangzhou 510462, China; National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China. Electronic address: wangheng2009@scau.edu.cn.

Journal Article , 2025

Cholesterol-dependent Nsp5-endosomes co-trafficking to lysosomes facilitates porcine reproductive and respiratory syndrome virus replication by activating autophagy.

Dong H; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Pei Q; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Ren J; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Zhang Y; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Wei X; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Shen A; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Lu Y; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Zhang Z; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Du Y; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Zhuang G; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China., Zhang A; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China; Ministry of Education Key Laboratory for Animal Pathogens and Biosafety, College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China. Electronic address: zhangangke1112@henau.edu.cn., Duan H; College of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China. Electronic address: duanhong0924@126.com.

Journal Article , 2025

Study of Hsp90α and Hsp90β role in virus replication using cell lines with Hsp90 gene knockouts.

Bieganowski P; Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland., Dalidowska I; Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland., Gazi O; Chair and Depatment of Medical Microbiology, Medical University of Warsaw, Warsaw, Poland., Guzowska M; Division of Biochemistry and Dietetics, Department of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, Poland., Przybylski M; Chair and Depatment of Medical Microbiology, Medical University of Warsaw, Warsaw, Poland. maciej.przybylski@wum.edu.pl.

Journal Article , 2025