Background: Schizophrenia is a long-lasting and debilitating mental health disorder that affects individuals globally. Recent studies by the World Health Organization (WHO) indicate that over 21 million individuals around the world are living with Schizophrenia.[1] Objectives: 1. To determine the frequency of attempts of suicide in schizophrenia. 2. To study and compare the various risk factors of suicide attempts in patients with schizophrenia. 3. To compare differences in the clinical and socio-demographic profile with and without suicide attempts in patients with schizophrenia. 4. To evaluate the relationship of severity, type and duration of schizophrenic illness among patients with and without suicide attempts. Materials and Methods: Study Design: Hospital-based descriptive crosssectional study. Study area: The study was conducted in the Department of Psychiatry, in a tertiary care teaching hospital. Study Period: 1 year. Study population: Participants were male and female patients diagnosed with Schizophrenia who came to the Psychiatry Department. Sample size: The study consisted of a total of 100 subjects. (27 attempted and 73 not attempted). Sampling Technique: convenience sampling method. Results: The mean score on the SAPS (positive symptoms scale) was 17.33 (SD - 7.68) for non-attempters, compared to 21.93 (SD - 9.20) for those with suicide attempts. The difference was statistically significant (P = 0.01) in the test. Conclusion: Suicide remains a significant risk for individuals with schizophrenia, particularly during the acute phases of the illness. Key risk factors include younger age, female gender, low income, alcohol use, and unemployment. Early identification, aggressive intervention, and sustained care beyond clinical recovery are crucial in mitigating this risk. Effective strategies involve treating depressive symptoms, improving treatment adherence, and maintaining vigilance, especially after significant losses. [ABSTRACT FROM AUTHOR]

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