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Academic Journal
Pharmacoeconomic study of the effectiveness of cytogenetic studies in patients with MM before prescribing first-line therapy
Yu. A. Zabolotneva, I. S. Krysanov
Качественная клиническая практика, Vol 0, Iss 4, Pp 40-51 (2024)
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| Title | Pharmacoeconomic study of the effectiveness of cytogenetic studies in patients with MM before prescribing first-line therapy |
|---|---|
| Authors | Yu. A. Zabolotneva, I. S. Krysanov |
| Publication Year |
2024
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| Source |
Качественная клиническая практика, Vol 0, Iss 4, Pp 40-51 (2024)
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| Description |
Purpose of the study. Conducting an assessment of the economic consequences (clinical and economic analysis) when conducting cytogenetic studies before prescribing various first-line treatment regimens for multiple myeloma (MM). Materialsand methods. The pharmacoeconomic study was carried out using the method of cost analysis, “cost-effectiveness” within the framework of the State Guarantee Program (SGP). Results. A review of the literature demonstrated that a limited number of data are currently available on the clinical effectiveness of the analyzed regimens in the first line, both in patients with normal and high cytogenetic risk. The cost-effectiveness analysis showed that among the three studied 1st-line treatment regimens (VMP, Rd, VRd), in terms of PFS (progression-free survival), the coefficient was minimal for the VMP regimen in patients with high cytogenetic risk. Conclusion. The study showed that the choice and prescription of first-line therapy, depending on the results of a cytogenetic study, is a clinically effective and cost-effective approach to organizing medical care for adult patients with multiple myeloma in the Russian Federation. This could be used in the future to formulate.
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| Document Type |
article
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| Language |
Russian
|
| Publisher Information |
Izdatelstvo OKI, 2024.
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| Subject Terms | |
