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Academic Journal
Relationship between endothelial function and platelet hemostasis in patients with a good compensation of type 2 diabetes mellitus and hypertension.
N. O. Pertseva
Морфологія, Vol 10, Iss 4, Pp 53-59 (2016)
Sparad:
| Titel | Relationship between endothelial function and platelet hemostasis in patients with a good compensation of type 2 diabetes mellitus and hypertension. |
|---|---|
| Författarna | N. O. Pertseva |
| Utgivningsår |
2016
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| Källa |
Морфологія, Vol 10, Iss 4, Pp 53-59 (2016)
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| Beskrivning |
Background. Disorders of hemostasis in patients with arterial hypertension and diabetes mellitus type 2 are complex: growing aggregative activity of platelets and red blood cells, activation and degranulation of platelet antiaggregatory potential endothelium; reduced anticoagulant and fibrinolytic activity of blood. Objective. The aim of this study is to determine the relationships between endothelial dysfunction, the degree of renal function damage, lipidemic profile and morphological changes of vascular-platelet hemostasis in patients with good compensation of type 2 diabetes mellitus and arterial hypertension.. Methods. In 69 patients with good glycemic compensation using clinical, laboratory, morphological methods and correlational analysis were identified association between endothelial dysfunction, degree of renal function damage, lipidemic profile and morphological changes of vascular-platelet hemostasis. Results. Results of correlation analysis showed the presence of credible negative relation between the content of unactivated platelets and concentrations of endothelin-1 (r=-0.53; p
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| Dokumenttyp |
article
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| Språk |
Russian
Ukrainian |
| Information om utgivare |
Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy, 2016.
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| Ämnestermer | |
