кислотозависимые состояния, гэрб, дуоденогастроэзофагеальный рефлюкс, функциональная диспепсия, эрадикационная терапия, постэрадикационная диспепсия, ингибиторы протонной помпы, омепразол, acid-base disorders, gerd, duodenogastroesophageal reflux, functio, Medicine

Proton pump inhibitors are the most effective treatment for all types of acid-base disorders. Despite differences between them, the available evidence demonstrated nearly the same clinical efficacy of various representatives of this group of drugs. Own experience with 115 patients with GERD 0-4 undergoing a treatment course with omeprazole, esomeprazole and rabeprazole at standard doses for 4 weeks showed high efficacy of all investigation drugs both in relation to symptom relief and healing erosions in the esophagus. The article demonstrates high efficacy of omeprazole (Omez) in the treatment of various acid-base disorders allowing to use it as the first-line therapy in most cases. Introduction of such forms as Omez Insta and Omez D allows to optimize treatment of GERD, DGER, FD and posteradication dyspepsia.