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Academic Journal
Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction
T. A. Denisuk, M. V. Pokrovskii, O. V. Philippova, O. S. Gudyrev, T. G. Pokrovskaya, M. V. Korokin, O. A. Osipova
Кубанский научный медицинский вестник, Iss 5, Pp 51-55 (2015)
Sparad:
| Titel | Endotelioand cardioprotective effects of HMG-Co-A reductase in endotoksininducing endotelial dysfunction |
|---|---|
| Författarna | T. A. Denisuk, M. V. Pokrovskii, O. V. Philippova, O. S. Gudyrev, T. G. Pokrovskaya, M. V. Korokin, O. A. Osipova |
| Utgivningsår |
2015
|
| Källa |
Кубанский научный медицинский вестник, Iss 5, Pp 51-55 (2015)
|
| Beskrivning |
The use of inhibitors of HMG-Co-A reductase inhibitor simvastatin, atorvastatin, rosuvastatin and nanoparticulative rosuvastatin on background modeling endotoksininducing pathology, introduction of strain 603 Staphylococcusaureus leads to the development of dose-response endotelioprotectiv action, expressed in the normalization of QED, prevent increase adrenoreactivity and exhaustion of myocardial reserve and and normalization of biochemical markers of inflammation (C-reactive protein) and the level of proinflammatory cytokines. When this is detected positive dynamics and-products of NO and expression of eNOS.
|
| Dokumenttyp |
article
|
| Språk |
Russian
|
| Information om utgivare |
Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”, 2015.
|
| Ämnestermer | |
