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Academic Journal
Hydrogel Tissue Bioengineered Scaffolds in Bone Repair: A Review
Qiteng Ding, Shuai Zhang, Xinglong Liu, Yingchun Zhao, Jiali Yang, Guodong Chai, Ning Wang, Shuang Ma, Wencong Liu, Chuanbo Ding
Molecules, Vol 28, Iss 20, p 7039 (2023)
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| Title | Hydrogel Tissue Bioengineered Scaffolds in Bone Repair: A Review |
|---|---|
| Authors | Qiteng Ding, Shuai Zhang, Xinglong Liu, Yingchun Zhao, Jiali Yang, Guodong Chai, Ning Wang, Shuang Ma, Wencong Liu, Chuanbo Ding |
| Publication Year |
2023
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| Source |
Molecules, Vol 28, Iss 20, p 7039 (2023)
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| Description |
Large bone defects due to trauma, infections, and tumors are difficult to heal spontaneously by the body’s repair mechanisms and have become a major hindrance to people’s daily lives and economic development. However, autologous and allogeneic bone grafts, with their lack of donors, more invasive surgery, immune rejection, and potential viral transmission, hinder the development of bone repair. Hydrogel tissue bioengineered scaffolds have gained widespread attention in the field of bone repair due to their good biocompatibility and three-dimensional network structure that facilitates cell adhesion and proliferation. In addition, loading natural products with nanoparticles and incorporating them into hydrogel tissue bioengineered scaffolds is one of the most effective strategies to promote bone repair due to the good bioactivity and limitations of natural products. Therefore, this paper presents a brief review of the application of hydrogels with different gel-forming properties, hydrogels with different matrices, and nanoparticle-loaded natural products loaded and incorporated into hydrogels for bone defect repair in recent years.
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| Document Type |
article
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| Language |
English
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| Publisher Information |
MDPI AG, 2023.
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| Subject Terms | |
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