Loading…
Academic Journal
Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study
María Hernández-García, Claudia Solito, Alba Pavón Ortiz, Noelia Arguedas Casamayor, Maria Melé-Casas, Gemma Pons-Tomàs, Mariona F. de Sevilla, Rosa Pino, Cristian Launes, Carmina Guitart, Mònica Girona-Alarcón, Iolanda Jordan, Juan José García-García
Children, Vol 10, Iss 10, p 1703 (2023)
Saved in:
| Title | Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study |
|---|---|
| Authors | María Hernández-García, Claudia Solito, Alba Pavón Ortiz, Noelia Arguedas Casamayor, Maria Melé-Casas, Gemma Pons-Tomàs, Mariona F. de Sevilla, Rosa Pino, Cristian Launes, Carmina Guitart, Mònica Girona-Alarcón, Iolanda Jordan, Juan José García-García |
| Publication Year |
2023
|
| Source |
Children, Vol 10, Iss 10, p 1703 (2023)
|
| Description |
SARS-CoV-2 pneumonia in children has a lower incidence and severity compared to adults. Risk factors are adolescence and comorbidities. Our aims were to describe the characteristics of children admitted with SARS-CoV-2 pneumonia, identify risk factors associated with severity and compare the cases according to the variant of SARS-CoV-2. This was a descriptive and retrospective study, including patients aged 0–18 years hospitalized in a tertiary-care hospital between 1 March 2020 and 1 March 2022. Epidemiological, clinical, diagnostic and therapeutic data were analyzed. Forty-four patients were admitted; twenty-six (59%) were male and twenty-seven (61%) were older than 12 years. Thirty-six (82%) had comorbidities, the most frequent of which were obesity and asthma. Seven (15.9%) patients required high-flow oxygen, eleven (25%) non-invasive ventilation and four (9.1%) conventional mechanical ventilation. In critically ill patients, higher levels of anemia, lymphopenia, procalcitonin, lactate dehydrogenase (LDH) and hypoalbuminemia and lower levels of HDL-cholesterol were detected (all p < 0.05). Prematurity (p = 0.022) was associated with intensive care unit admission. Patients were younger during the Omicron wave (p < 0.01); no variant was associated with greater severity. In conclusion, pediatric patients with a history of prematurity or with anemia, lymphopenia, elevated procalcitonin, elevated LDH levels, hypoalbuminemia and low HDL-cholesterol levels may require admission and present more severe forms. Apart from age, no notable differences between SARS-CoV-2 variant periods were found.
|
| Document Type |
article
|
| Language |
English
|
| Publisher Information |
MDPI AG, 2023.
|
| Subject Terms | |
