急性缺血性卒中, 醒后卒中, 发病时间, 影像学, 人工智能, acute ischemic stroke, wake-up stroke, onset time, imaging, artificial intelligence, Neurology. Diseases of the nervous system, RC346-429

急性缺血性卒中超急性期治疗的重点是再灌注治疗，且再灌注治疗具有严格的时间依赖性。而醒后卒中患者由于发病时间不明确，其再灌注治疗决策面临挑战。本文对急性缺血性卒中患者发病时间评估的研究进展进行综述，涵盖了基于昼夜节律、影像学和人工智能的评估方法，分析了不同方法评估急性缺血性卒中患者发病时间的效能，以期为醒后卒中患者再灌注治疗的选择提供支持依据。 Abstract: The focus of acute ischemic stroke treatment in the hyperacute phase is reperfusion therapy, which is strictly time-dependent. However, patients with wake-up stroke face challenges in reperfusion therapy decisions due to the unclear onset time of the disease. This article reviews the research progress in assessing the onset time of acute ischemic stroke patients, covering assessment methods based on circadian rhythms, imaging, and artificial intelligence. It analyzes the efficacy of different methods in assessing the onset time of acute ischemic stroke patients, aiming to apply these findings to wake-up stroke patients, providing a supportive basis for the selection of their reperfusion therapy.