Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 27, Iss 1, Pp 50-61 (2018)

диспепсия, функциональная диспепсия, органическая диспепсия, хронический гастрит, инфекция helicobacter pylori, эрадикация, Diseases of the digestive system. Gastroenterology, RC799-869

The aim of publication. To present the modern concept on etiology and pathogenesis of functional dyspepsia (FD) to general practitioners, as well as with the accepted approach to diagnostics and treatment of this disease. Summary. FD is the most common digestive disease. It’s etiology includes genetic predisposition, bad habits, previous intestinal infections, psychosocial factors. The basic pathogenic factors may include HCl hypersecretion, stomach and duodenal dysmotility and visceral hypersensitivity. FD diagnosis should be established after ruling out of the organic diseases that may manifest by dyspepsia. Treatment is based on the stepwise approach, that includes general procedures, application of the drugs reducing hydrochloric acid secretion and normalizing motility and visceral sensitivity of the stomach and duodenum, in difficult to treat cases - psychopharmacological drugs and psychotherapeutic methods. Conclusion. Following of the functional dyspepsia management algorithm allows to increase the accuracy of FD diagnosis and improve treatment results.