CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial - Raymond Stegeman; Maaike Nijman; Johannes M. P. J. Breur; Floris Groenendaal; Felix Haas; Jan B. Derks; Joppe Nijman; Ingrid M. van Beynum; Yannick J. H. J. Taverne; Ad J. J. C. Bogers; Willem A. Helbing; Willem P. de Boode; et al. (Trials, 2022)