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Academic Journal
Subpopulation structure of regulatory Т-cells of blood in patients with multiple drugresistant pulmonary tuberculosis
Ye. G. Churina, V. V. Novitsky, O. I. Urazova, O. V. Voronkova, Yu. V. Kolobovnikova
Бюллетень сибирской медицины, Vol 10, Iss 4, Pp 183-187 (2011)
Sparad:
Titel | Subpopulation structure of regulatory Т-cells of blood in patients with multiple drugresistant pulmonary tuberculosis |
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Författarna | Ye. G. Churina, V. V. Novitsky, O. I. Urazova, O. V. Voronkova, Yu. V. Kolobovnikova |
Utgivningsår |
2011
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Källa |
Бюллетень сибирской медицины, Vol 10, Iss 4, Pp 183-187 (2011)
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Beskrivning |
Subpopulation structure of regulatory T-cells of peripheral blood in patients with newly diagnosed pulmonary tuberculosis depending on the clinical form of disease and sensitivity of Mycobacterium tuberculosis to anti-tuberculosis drugs have been analyzed in this work. It has been shown that in formation immune suppression at infiltrative, dissemination and fibrosis-cavity pulmonary tuberculosis the leading part play natural regulatory CD4+ CD25+ Foxр3+ -T-lymphocytes. Thus increase of their number in blood at drug-resistance and drugsusceptible patients. It has been demonstrated that in patients with fibro-cavernous and infiltrative form of the disease and drug-resistance pulmonary tuberculosis the number of CD4+ CD25- Foxр3+ -regulatory T-cells were increasing.
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Dokumenttyp |
article
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Språk |
English
Russian |
Information om utgivare |
Siberian State Medical University (Tomsk), 2011.
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Ämnestermer | |