Intrahepatic cholangiocarcinoma, Inverse probability of treatment weighted analysis, Hepatology, Lymph node biology, Lymph node dissection, Propensity score matching analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Abstract Purpose Intrahepatic cholangiocarcinoma (ICC) is an extremely deadly cancer with high recurrence incidence, particularly in patients with lymph node metastasis (LNM). The necessity of lymphadenectomy including lymph node biology (LNB) and dissection (LND) during ICC radical surgery remains debate. Methods We retrospectively analyzed the patients diagnosed with ICC and underwent radical surgery at the Cancer Hospital of the Chinese Academy of Medical Sciences from 2012 to 2023. Results A total of 308 ICC patients were involved in this study. pLNM+ group had poorer OS (P