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Academic Journal
The role of polymorphism of genes eotaxin (–384) and CCR3 (–51) in formation of blood eosinophilia under pulmonary tuberculosis
K. O. Miheeva, Yu. V. Kolobovnikova, O. I. Urazova, V. V. Novitsky, O. V. Filinyuk, M. D. Goncharov, I. O. Naslednikova
Бюллетень сибирской медицины, Vol 11, Iss 6, Pp 213-215 (2012)
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| Title | The role of polymorphism of genes eotaxin (–384) and CCR3 (–51) in formation of blood eosinophilia under pulmonary tuberculosis |
|---|---|
| Authors | K. O. Miheeva, Yu. V. Kolobovnikova, O. I. Urazova, V. V. Novitsky, O. V. Filinyuk, M. D. Goncharov, I. O. Naslednikova |
| Publication Year |
2012
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| Source |
Бюллетень сибирской медицины, Vol 11, Iss 6, Pp 213-215 (2012)
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| Description |
With attracting contemporary molecular-genetic and immunological research methods, it has been established that blood eosinophilia under pulmonary tuberculosis is mediated by hypersecretion eotaxin. Susceptibility to the emergence of eosinophilic blood reaction under tubercular infection is associated with the allele G and homozygous genotype GG of the polymorphic region A-384G of the gene eotaxin as well as with allele С and homozygous genotype СС polymorphism T-51C of the gene ССR3.
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| Document Type |
article
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| Language |
English
Russian |
| Publisher Information |
Siberian State Medical University (Tomsk), 2012.
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| Subject Terms | |
