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Academic Journal
Monoclonal Antibodies and Recombinant Proteins for Immune-Diagnostics of Ebola Virus Disease
E. I. Kazachinskaya, Yu. V. Nikonorova, V. B. Loktev
Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 58-64 (2015)
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| Title | Monoclonal Antibodies and Recombinant Proteins for Immune-Diagnostics of Ebola Virus Disease |
|---|---|
| Authors | E. I. Kazachinskaya, Yu. V. Nikonorova, V. B. Loktev |
| Publication Year |
2015
|
| Source |
Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 58-64 (2015)
|
| Description |
The review summarizes the literature data on the studies of viral antigens and antibodies, specific to Ebola virus, suitable for the development of a test-system for immune-diagnostics of the disease caused by them. Represented are the results of investigations on the obtainment of hybridoma monoclonal antibodies (MCA), specific to structural viral proteins NP, VP40, and VP35; recombinant proteins NP, VP40, and VP35 in prokaryotic system of E. coli; as well as the possibility to utilize MCA panels for EV viral and recombinant proteins’ detection in ELISA.
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| Document Type |
article
|
| Language |
Russian
|
| Publisher Information |
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”, 2015.
|
| Subject Terms | |
