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Academic Journal
Effects of lithium ascorbate in middle-aged patients with stenosing atherosclerosis of brachiocephalic arteries
E. A. Pepelyaev, V. A. Semenov, I. Yu. Torshin, O. A. Gromova
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 42-49 (2018)
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| Title | Effects of lithium ascorbate in middle-aged patients with stenosing atherosclerosis of brachiocephalic arteries |
|---|---|
| Authors | E. A. Pepelyaev, V. A. Semenov, I. Yu. Torshin, O. A. Gromova |
| Publication Year |
2018
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| Source |
Фармакокинетика и Фармакодинамика, Vol 0, Iss 4, Pp 42-49 (2018)
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| Description |
Resume. Lithium ascorbate is a highly digestible and low-toxic lithium salt. In stis study patients with stenosing arteriosclerosis of brachiocephalic arteries were under observation (n = 70, mean age 52 years, 50 % men). In group A (n = 30), participants received standard therapy and lithium ascorbate (0.78 mg/day of elemental lithium, 8 weeks), in group B (n = 40, control) - only the standard therapy. Effects of the lithium ascorbate on the results of neuropsychological testing (Luria's technique, Schulte tables, MMSE and BDI scales, visual-spatial gnosis), levels of BDNF and the levels of trace elements in hair have been established. Lithium ascorbate contributed to a significant improvement in work capacity, mood, a decrease in the proportion of patients with 20 % cerebral stenosis, increased levels of BDNF and a decrease in the levels of toxic trace elements in the hair.
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| Document Type |
article
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| Language |
Russian
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| Publisher Information |
LLC “Publisher OKI”, 2018.
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| Subject Terms | |
