Triglyceride-glucose index, Premature coronary artery disease, Insulin resistance, Prognosis, Major adverse cardiovascular events, Cohort study, Diseases of the circulatory (Cardiovascular) system, RC666-701

Abstract Background Premature coronary artery disease (PCAD) has become more common in recent years and is often associated with poor outcomes. Triglyceride-glucose (TyG) index is a simple and reliable surrogate for insulin resistance (IR) and is an independent predictor of cardiovascular prognosis. However, the prognostic value of the TyG index in patients with PCAD remains uncertain. Thus, this study aimed to investigate the prognostic value and predictive performance of the TyG index in patients with PCAD. Methods A total of 526 young subjects (male