Association between triglyceride glucose body mass index and cardiovascular disease in adults: evidence from NHANES 2011- 2020

2024

Frontiers in Endocrinology, Vol 15 (2024)

BackgroundThe association between insulin resistance and cardiovascular diseases (CVD) is of significant interest. However, there is limited published research on the relationship between CVD and the triglyceride glucose-body mass index (TyG-BMI). This study aims to examine the association between TyG-BMI and CVD in US adults.MethodWe analyzed data from 11016 adults collected through the 2011-2020 NHANES. Employing weighted generalized linear models, subgroup analysis, sensitivity analysis, and receiver operating characteristic curves, we examined the association between the TyG-BMI index and CVD. Nonlinear associations were investigated using restricted cubic splines.ResultsHigher TyG-BMI values were significantly associated with an increased prevalence of CVD (P0.05). Incorporating the TyG-BMI index into traditional risk factor models marginally improved the prediction of CVD prevalence (P for comparison

article

English

Frontiers Media S.A., 2024.

cardiovascular disease, TyG-BMI, insulin resistance, NHANES, cross-sectional studies, Diseases of the endocrine glands. Clinical endocrinology, RC648-665