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Academic Journal
Generation of a hiPSC line ZZUNEUi007-A from a patient with hypertrophic cardiomyopathy caused by mutation in MYH7
Xiaowei Li, Yangyang Liu, Feifei Liu, Xiaojuan Wang, Mengduan Liu, Wenting Du, Jing Zhao, Mengyu Wang, Liang Hu, Chuchu Wang, Wanrong Fu, Jianzeng Dong, Xiaoyan Zhao
Stem Cell Research, Vol 43, Iss , Pp - (2020)
Sparad:
| Titel | Generation of a hiPSC line ZZUNEUi007-A from a patient with hypertrophic cardiomyopathy caused by mutation in MYH7 |
|---|---|
| Författarna | Xiaowei Li, Yangyang Liu, Feifei Liu, Xiaojuan Wang, Mengduan Liu, Wenting Du, Jing Zhao, Mengyu Wang, Liang Hu, Chuchu Wang, Wanrong Fu, Jianzeng Dong, Xiaoyan Zhao |
| Utgivningsår |
2020
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| Källa |
Stem Cell Research, Vol 43, Iss , Pp - (2020)
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| Beskrivning |
Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiovascular disorder. In this study, we generated human induced pluripotent stem cells (iPSC) ZZUNEUi007-A from dermal fibroblasts of an HCM patient with the p. R663H (c. 1988 G > A) mutation in MYH7. The generated hiPSC line had normal karyotype, showed robust expression of pluripotency markers and could differentiate into all three germ layers in vivo.
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| Dokumenttyp |
article
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| Språk |
English
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| Information om utgivare |
Elsevier, 2020.
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| Ämnestermer | |
