пародонтит, маркер, ротовая жидкость, матриксные металлопротеиназы, интерлейкин, фактор некроза, опухоли, periodontitis, marker, oral fluid, matrix metalloproteinases, interleukin, tumor necrosis factor, Medicine

The relationship between inflammatory markers in the oral fluid of patients with chronic generalized periodontitis and the main clinical manifestations of the disease is demonstrated. An enzyme immunoassay for the detection of MMP-8, MMP-9, MMP-2, IL-1β, TNF-α was carried out. The results validly demonstrated the informative value of biochemical indicators MMP-2, MMP-8, MMP-9 for dianosing periodontitis.