Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 8504688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3449 (Electronic) Linking ISSN: 07492081 NLM ISO Abbreviation: Semin Oncol Nurs Subsets: MEDLINE

Neoplasms*/nursing , Neoplasms*/psychology , Social Support* , Parents*/psychology , Caregivers*/psychology , Psychological Distress* , Caregiver Burden*/psychology, Humans ; Male ; Female ; Adult ; Child ; Iran ; Middle Aged ; Surveys and Questionnaires ; Child, Preschool ; Cross-Sectional Studies ; Adolescent ; Adaptation, Psychological ; Cost of Illness

Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Objectives: This study aimed to explore the predictors of caregiver burden among parents of children with cancer.
Methods: A descriptive correlational study was conducted on 254 parents of children with cancer in the oncology department of Baghaei 2 Hospital in Ahvaz, Iran from September 2022 to July 2023. The study's data was collected through the demographic information questionnaire, the caregiver burden scale (CBS), the perceived social support (PSS), and the General Health Questionnaire (GHQ). Data were analyzed using an independent t-test, 1-way ANOVA, Pearson's correlation coefficient, and multiple linear regression in SPSS-22.
Results: Parents experienced a moderate level of CBS (54.74 ± 10.17), PSS (41.52 ± 12.94), and GHQ (18.95 ± 4.47). Regression models showed that PSS (β = -0.381, P < .001), GH (β = 0.199, P < .001), caregiving responsibilities for others (β = 0.195, P < .001), satisfaction with income (β = -0.151, P = .005), and hospitalization number (β = 0.142, P = .007) were significantly associated with the CB of parents of children with cancer. These variables accounted for 32% of the variance in CB.
Conclusion: This study demonstrated various degrees of CB among parents of children with cancer. A better understanding of the predictive factors of CB is needed to provide suitable interventions such as caregiving skills, and coping strategies to alleviate CB among parents and subsequently improve the quality of caregiving.
Implication for Nursing Practice: Pediatric oncology nurses should adopt a holistic approach that addresses both the emotional and social needs of parents, in addition to the medical needs of the child. Developing support programs tailored to parents' experiences, educating them on managing caregiving challenges, and facilitating effective communication regarding treatment processes can help alleviate parental CB.
(Copyright © 2025 Elsevier Inc. All rights reserved.)