The composition of the astrophysical relativistic jets remains uncertain. By kinetic particle-in-cell simulations, we show that the baryon component in the jet, or the so-called baryon loading effect (BLE), heavily affects relativistic jets transport dynamics in the interstellar medium. On the one hand, with the BLE, relativistic jets can transport in a much longer distance, because jet electrons draw a significant amount of energy from jet baryons via the Buneman-induced electrostatic waves and the Weibel-mediated collisionless shock; on the other hand, the jet electron phase space distribution may transform from a bottom-wide-single-peak structure to a center-wide-multiple-peak one by increasing the BLE, which largely influences the observed jet morphology. Implications for related astrophysical studies are also discussed.