The process of electron-positron pair creation through multi-photon absorption in a space-time dependent electric field is analyzed using computational quantum field theory. Our findings reveal two distinct pair creation channels: the symmetric and asymmetric transition channels. We propose that the asymmetric transition channel arises from the inherent spatial inhomogeneity of intense laser pulses. By mapping the field-theoretical model of laser-assisted multi-photon pair creation onto a quantum-mechanical time-dependent framework, a semi-analytical solution that captures the asymmetric transition signatures of vacuum decay is derived. Additionally, it is demonstrated that neglecting spatial inhomogeneity leads to erroneous transition amplitudes and incorrect identification of pair creation channels. Furthermore, we have established that asymmetric transition channels substantially enhance the creation of electron-positron pairs for a given laser pulse energy.