meconium metabolome, untargeted metabolomics, LC-HRMS, day-to-day variations, sphingolipids, sphingolipidomics, sphingoid bases, lipidomics, mass spectrometry, bile acids, UPLC–Q-TOF, wet feces, sulfation, isomerization, BA indices, liquid chromatography–mass spectrometry, time-of-flight, steroid hormones, androgens, urinary extracellular vesicles, hormone-dependent disease, metabolomics, metabolomics extraction, signaling lipids, polar metabolites, muscle tissue, muscle ageing and sarcopenia, human urine, liquid chromatography, untargeted mass spectrometry, computational metabolomics, chemometrics, bioinformatics, GC–IMS, urine, volatile organic compounds, volatilomics, fatty acids, boar taint, gas chromatography, GC×GC–TOFMS, pentose phosphate pathway, triose phosphates, acetyl-CoA, lipogenesis, 13C NMR, non-enzymatic glycation, Maillard reaction products, HILIC-MS, untargeted analysis, advanced glycation end products, saliva, ATR-FTIR, sample processing, Raman, Research and information: general, Biology, life sciences

This reprint is a collection of articles belonging to the Special Issue Advances in Metabolic Profiling of Biological Samples of Metabolites. The Special Issue is dedicated to reviews and original articles covering the current methodological and technological advancements in the pre-analytical handling of biological samples, sample preparation protocols, analytical approaches for untargeted and targeted metabolic profiling, and metabolite annotation tools.