Assisted pregnancy, Assisted reproductive technology, In-vitro fertilisation, Intra-uterine insemination, Pregnancy outcome, Neonatal outcome, Gynecology and obstetrics, RG1-991

Abstract Background Assisted reproductive techniques are increasingly used to achieve fertility in developing countries in South Asia. However, the data on the outcome of assisted pregnancies are sparse. This study aims to evaluate the pregnancy, delivery and neonatal outcomes and complications of assisted pregnancies in Sri Lanka, a low-middle-income country in South Asia. Methods We performed a secondary analysis of the data of the island-wide multi-centre Sri Lanka Birth Weight Study, which recruited all live-born newborns in 13 hospitals covering 20% of all births in the country from 01 August to 30 September 2023. Data on socio-demographic background, type of conception, pre-pregnancy medical, obstetric and delivery complications and immediate neonatal outcomes were collected by interviewing mothers and perusing patient records. Maternal age-, multiple births- and prematurity-adjusted odds ratios were determined by logistic regression analysis. Results Of the 8992 pregnancies, 8900 (99.0%) were spontaneous conceptions. The assisted pregnancy rate was 1.0%, with 52 intra-uterine insemination and 40 in-vitro fertilisation pregnancies. The mean ages of mothers who had intra-uterine insemination (31.2 years) or in-vitro fertilisation (38.7 years) were significantly (p