Eco-friendly feed, Entero-hepatic health, Sustainable aquaculture, Chinese herbal medicine, High-density intensive aquaculture, Aquaculture. Fisheries. Angling, SH1-691

Intestinal inflammation and hepatic fat accumulation syndrome is a major issue in farmed fish. In this study, grass carp (20.3 ± 0.1 g) were fed for 8 weeks with six feeds containing different Pennisetum sinese Roxb meal (PSRM) levels (0, 5, 10 %) and 0 or 0.1 % berberine (BBR). Growth remained unaffected by BBR and PSRM. PSRM reduced the CF, HI, and VSI, whereas BBR had no such effect or interaction. PSRM (not BBR) suppressed the activities of serum AST and ALT, as well as the contents of LDL - c, T - CHO, and TG (P