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Academic Journal
The antiarrhythmic activity comparative study of Lappaconitine hydrobromide and LMG-124 on the model of aconitine arrhythmia
V. N. Stolyaruk, I. B. Tsorin, M. B. Vititnova, T. D. Nikiforova, Yu. I. Murinov, M. S. Yunusov, S. A. Kryzhanovskii
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 12-15 (2017)
Sparad:
| Titel | The antiarrhythmic activity comparative study of Lappaconitine hydrobromide and LMG-124 on the model of aconitine arrhythmia |
|---|---|
| Författarna | V. N. Stolyaruk, I. B. Tsorin, M. B. Vititnova, T. D. Nikiforova, Yu. I. Murinov, M. S. Yunusov, S. A. Kryzhanovskii |
| Utgivningsår |
2017
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| Källa |
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 12-15 (2017)
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| Beskrivning |
Two models of the aconitin-induced cardiac arrhythmias were used to compare the antiarrhythmic and antifibrillatory activity of the reference drug Lappaconitine hydrobromide and the LMG-124 compound. It is shown that both compounds have antiarrhythmic action. At the same time, the compound LMG-124 realizes its antiarrhythmic effect in a significantly lower dose. In this case, the compound LMG-124 shows a pronounced antifibrillatory activity, in contrast to the reference drug Lappaconitine hydrobromide, which in the studied dose does not exhibit similar activity.
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| Dokumenttyp |
article
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| Språk |
Russian
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| Information om utgivare |
LLC “Publisher OKI”, 2017.
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| Ämnestermer | |
