Body Mass Index, POSEIDON criteria, Pregnancy Outcomes, In Vitro Fertilization/IntraCytoplasmic Sperm Injection, Gynecology and obstetrics, RG1-991

Abstract Background The aim of this study was to investeigate the pregnancy outcomes of young women with low prognosis according to the POSEIDON criteria after IVF/ICSI cycles and to explore the effect of body mass index (BMI) on pregnancy outcomes. Methods This was a retrospective cohort study conducted in women who underwent their first IVF/ICSI cycle treatment between January 2018 and December 2020, Among them, these patients who met criteria for POSEIDON group1and 3 were further categorized into four groups according to the China body mass index(BMI) classification, we analyzed the effect of BMI on pregnancy outcomes. Results A total of 29,354 patients were conducted first IVF/ICSI cycle between January 2018 and December 2020 in our reproductive center, 5981 women who met the criteria for POSEIDON 1 and POSEIDON 3 were further categorized into four groups according to the China body mass index(BMI) classification. There were not significant differences in the implantation rate and clinical pregnancy rate, regardless of fresh embryo transfer or frozen embryo transfer among the four groups (P > 0.05). The miscarriage rate of fresh embryo transfer was significantly higher in obese patients (P