Realizing the superior stability of natural resources for regional economic growth depends on the construction of the Ecological Security Pattern (ESP)11 the Ecological Security Pattern (ESP).. The ESP of Hubei Province was determined based on the supply and demand of ecosystem services (ESSD)22 the supply and demand of ecosystem services (ESSD).. The main conclusions are as follows: (1) The overall supply of ecosystem services in Hubei Province exceeds the demand, and the imbalance between supply and demand in Wuhan, Xiangyang and Jingzhou is the most serious. (2) The largest ecological source area in 2000 was 90,506 km2, followed by 86,946 km2 in 2020. (3) 11 long-term ecological obstacles with a total area of 312.96 km2 were identified, which were mainly composed of large areas of cultivated land and water. (5) The ecological protection and restoration pattern of “two axes, three belts, four districts and five cores (two main and three secondary)” has been constructed in Hubei Province. The results of this study provide reference for the management and protection of regional ecosystem and the overall response to ecological problems in Hubei Province.