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Academic Journal
THE EVOLUTION OF UNDERSTANDING OF THE IMMUNE SYSTEM'S ROLE IN THE PATHOGENESIS OF INFLAMMATORY MYOCARDIAL DISEASES: TH17-MEDIATED IMMUNE MECHANISMS
N. R. Paleev, P. N. Paleev, E. I. Ostrovsky, V. I. Karandashov, N. P. Sanina, N. N. Khishova, O. V. Moskalets, A. P. Linnik, A. N. Makarkov
Кубанский научный медицинский вестник, Vol 0, Iss 1, Pp 191-195 (2014)
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Title | THE EVOLUTION OF UNDERSTANDING OF THE IMMUNE SYSTEM'S ROLE IN THE PATHOGENESIS OF INFLAMMATORY MYOCARDIAL DISEASES: TH17-MEDIATED IMMUNE MECHANISMS |
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Authors | N. R. Paleev, P. N. Paleev, E. I. Ostrovsky, V. I. Karandashov, N. P. Sanina, N. N. Khishova, O. V. Moskalets, A. P. Linnik, A. N. Makarkov |
Publication Year |
2014
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Source |
Кубанский научный медицинский вестник, Vol 0, Iss 1, Pp 191-195 (2014)
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Description |
The review article discusses recent advances in our understanding of viral myocarditis such as pathogenic role of infection and immune mechanisms in acute, sub-acute and chronic phases of the disease. A newly discovered Th17 lymphocyte subset and Interleukin 17 play an important role in the development of inflammatory myocardial diseases. The protective effect of Interferon y and Th1 immune response in acute myocarditis and the role of Th17-mediated mechanisms in progression of acute myocarditis to dilated cardiomyopathy are considered. The evidence of pathogenic role of Th17 lymphocytes in viral myocarditis in human is given.
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Document Type |
article
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Language |
Russian
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Publisher Information |
Ministry of Healthcare of the Russian Federation. “Kuban State Medical University”, 2014.
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Subject Terms | |