Type 1 diabetes mellitus, Myocardial strain, Myocardial perfusion, Cardiac magnetic resonance, Glycemic control, Diseases of the circulatory (Cardiovascular) system, RC666-701

Abstract Background Cardiovascular disease remains the leading cause of morbidity and mortality among individuals with type 1 diabetes mellitus (T1DM). Individuals with hyperglycemia are at great risk of cardiovascular complications. This study investigated the impact of glycemic control on left ventricular (LV) microvascular perfusion and myocardial deformation in uncomplicated pediatric T1DM using cardiac magnetic resonance (CMR) imaging. Methods A total of 100 uncomplicated pediatric patients with T1DM and 35 controls were enrolled and underwent 3.0 T CMR examinations. Patients were divided into two groups according to HbA1c levels of 7.0% (HbA1c