псориаз, озонотерапия, озонированный физиологический раствор, плазмаферез, Medicine

Aim: to study the efficacy of autotransfusion of ozone modified erythrocyte suspension in the complex therapy of extensive psoriasis. 118 patients with progressive stage of extensive psoriasis from the age of 18 to 66 have been investigated. Clinical picture, some indices of coagulogram, protein metabolism, lipid peroxidation and antioxidant protection processes in blood plasma have been studied in dynamics. Inclusion of ozonetherapy in the complex treatment of psoriasis contributed to the more rapid and complete positive dynamics of skin process, decreasing of seromucoid and С-reactive protein level, correction of some impaired coagulogram indices, normalization of the lipid peroxidation process level. The use of plasmapheresis with autotransfusion of ozone modified erythrocyte suspension appears to be the most effective. The tolerability of the procedures was good.