biopsy, central pulmonary lesions (CPLs), computed tomography–guided percutaneous transthoracic needle biopsy (PTNB), electronic bronchoscopy–guided transbronchial lung biopsy (TBLB), pathological diagnosis, Diseases of the respiratory system, RC705-779

ABSTRACT Background Lung cancer is one of the most common malignant tumors at present. This study aimed to compare the diagnostic accuracy, complication rates, and predictive values of computed tomography (CT)–guided percutaneous transthoracic needle biopsy (PTNB) and electronic bronchoscopy–guided transbronchial lung biopsy (TBLB) for patients with central pulmonary lesions (CPLs) with a diameter ≥ 3 cm. Methods We retrospectively included 110 patients with CPLs with a diameter ≥ 3 cm who underwent preoperative PTNB and TBLB examinations and ultimately underwent surgery to remove CPLs and obtained pathological results. Detailed information was collected in order to compare whether there was a difference between two groups. Data were processed using SPSS software (Version 26.0; IBM Corp). Data were compared by t‐test or chi‐square test. p