β-blockers, bronchial asthma, chronic obstructive pulmonary disease, bisoprolol, spirometry testing, airway conductance, bronchial provocation test, β-блокаторы, бронхиальная астма, хроническая обструктивная болезнь легких, бисопролол, спирометрия, бронхиальная проводимость, бронхопровокационный тест, Medicine

Administration of β-blockers in patients with cardiovascular pathology combined with obstructive bronchial or pulmonary disease (bronchial asthma (BA) and chronic obstructive pulmonary disease (COPD)) is associated with a risk of bronchospasm in a number of patients. No test has been developed so far to identify such patients. We recommend to carry out a 4-hour bronchial provocation test with a small dose of beta 1 selective β-blocker bisoprolol. The study included 31 patients with BA and COPD with concomitant cardiovascular disease requiring administration of β-blockers. Results of six consecutive spirometry tests, which continued for 4 hours to assess the effect of bisoprolol on airway function, are demonstrated. The maximum reduction in FEV1 after administration of the β-blocker was identified. Spirometry test results were compared in patients with BA and COPD.