Antiaggregant impact of vascular wall on hemocyte in hypertension patients with dyslipidemia taking simvastatin

2012

RUDN Journal of Medicine, Vol 0, Iss 4, Pp 39-46 (2012)

The work purpose — to define at patients with an arterial hypertension with a dyslipidemia extent of influence simvastatin on antiaggregatory control from vessels over erythrocytes, platelets and leukocytes. The arterial hypertension registered at patients with a dyslipidemia the strengthened aggregation of erythrocytes, platelets and neutrophils develops against decrease in control over it from the vascular wall, arising in many respects at the expense of violations in a lipidic exchange, activation of oxidation of lipids of plasma and weakening of generation of oxide of nitrogen and education prostacyclin. As a result of 104 week applications simvastatin at patients with an arterial hypertension with a dyslipidemia normalization of lipidic structure, processes of lipid peroxidation in plasma and blood cells and antiaggregatory ability of a vascular wall is reached.

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Peoples’ Friendship University of Russia (RUDN University), 2012.

артериальная гипертония, дислипидемия, симвастатин, антиагрегационная активность сосудистой стенки, эритроциты, тромбоциты, нейтрофилы, Medicine