Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 22, Iss 3, Pp 20-24 (2015)

мелатонин, хирургические болезни, предоперационный период, иммунологическая коррекция, интерлейкины, melatonin, surgical disease, preoperative period, immunological correction, interleukins, Medicine (General), R5-920

Since the widespread introduction of minimally invasive laparoscopic techniques in abdominal surgery there was a question - what are their physiological differences from operations withapproach by laparotomy. The study of these differences, mechanisms and their correction allows you to bring the results of operations with open approach to the laparoscopic. However, the possibility of an effective systemic exposure, allowing adapting body reaction to surgical procedures remains unresolved. To date, the use of melatonin in surgical practice is based on its functions as a neurotransmitter that can potentiate some natural protective reaction of the body. The paper analyzes the effects of melatonin, you can use as a biological adaptogenic control which generally acts as a trigger to launch a diver-seprocesses, including reparative ones in the body. The use of adaptive mechanisms initiated by melatonin in response to surgical trauma and tumor processes can be successfully applied to improve the results of surgical treatment of patients with surgical diseases operated as open and laparoscopic access.