Urinary tract endometriosis, Health-related quality of life, Physical health, Mental health, SF-12, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270

Abstract Background Urinary tract endometriosis (UTE) is a special type of endometriosis affecting the urinary system, yet the physical and mental health of UTE patients remain unexplored. Methods We enrolled 92 women with UTE and another 234 with deep infiltrating endometriosis from the First Affiliated Hospital of Sun Yat-sen University. Personal information was collected via paper questionnaires. Health-related quality of life, including physical and mental health, was measured by physical component summary scale (PCS) and mental component summary scale (MCS) of the 12-item Short Form Health Survey (SF-12). Multiple linear regression analysis was conducted to identify factors influencing physical and mental health. Results Patients in the UTE group had a higher creatinine level and detection rate of urinary leukocyte, erythrocyte and protein. The PCS score was lower in the UTE group, while the MCS was similar between two groups. Multiple linear regression analysis shown that patients using painkillers had lower PCS scores, while those aware of urologic abnormalities before surgery or with a history of more than two miscarriages had lower MCS scores. Conclusions Our study explores the quality of life in UTE patients and identifies influencing factors. Individualized and targeted care should be added to clinical practice to prevent negative outcomes for UTE patients.