синдром поликистозных яичников, женщины репродуктивного возраста, овариальный резерв, антимюллеров гормон, фенотипы, polycystic ovary syndrome, reproductive age, ovarian reserve, anti-müllerian hormone, phenotypes, Medicine (General), R5-920

Aim. To study the ovarian reserve in women of reproductive age with polycystic ovary syndrome (PCOS). Materials and Methods. We recruited 200 women of reproductive age with and without PCOS (n = 100 per group) and performed a comprehensive clinical, gynecological, laboratory, and ultrasound examination. Results. We found that 53% women had a major (A) polycystic ovary syndrome phenotype. Anti-Mullerian hormone (AMH) index was high in women with main (A) and non-androgenic (D) PCOS phenotypes but within the reference values in those with anovulatory (B) and ovulatory (C) phenotypes and healthy women. Ultrasound parameters of the ovaries in women with main (A), ovulatory (C) and non-androgenic (D) PCOS phenotypes were significantly higher compared to those with anovulatory (B) phenotype and healthy women. Conclusions. Ovarian reserve in women of reproductive age with PCOS significantly differs between its phenotypes and as compared to healthy women.