трифтазин, вальпроевая кислота, фетальный вальпроатный синдром, расстройства аутистического спектра, социальное взаимодействие, тревожность, triftazin, valproic acid, fetal valproate syndrome, autism spectrum disorders, social interaction, anxiety, Pharmacy and materia medica, RS1-441

The effect of triftazin (trifluoperazine) on social interaction abnormalities as a main feature of autism spectrum disorders, exploratory behavior and learning capacity was studied in rats with fetal valproatate syndrome. It was shown that triftazin at a dose of 0,35 mg/kg does not affect the deficit of social interaction, spatial learning or memory but improves exploratory activity by decreasing anxiety in rats with fetal valproate syndrome.