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Academic Journal
Role of steroid hormones, estrogen receptors and metabolites in the development of endometrial hyperplasia and carcinoma
A. L. Chernyshova, L. A. Kolomiets, S. L. Stucanov
Бюллетень сибирской медицины, Vol 11, Iss 6, Pp 172-177 (2012)
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| Title | Role of steroid hormones, estrogen receptors and metabolites in the development of endometrial hyperplasia and carcinoma |
|---|---|
| Authors | A. L. Chernyshova, L. A. Kolomiets, S. L. Stucanov |
| Publication Year |
2012
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| Source |
Бюллетень сибирской медицины, Vol 11, Iss 6, Pp 172-177 (2012)
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| Description |
The integrated study of the level of hormones in systemic circulation, estrogen reception and metabolism in patients with endometrial hyperplasia and endometrial cancer has shown that the urinary level of estrogen metabolites in patients with hyperplastic and malignant endometrium depends on the level of steroid hormones in systemic circulation. The study showed that the changes in hormonal status were characterized by a high frequency of disturbances with development of hyperestrogenemia, hypertestosteronemia. Moreover, the LH level and LH/FSH index were increased and FSH and progerterone levels were decreased. Correlation between the level of steroid hormone receptors and the level of estrogen metabolites has been identified. It confirms the theory of “estrogen” stimulation recommended for patients with proliferative endometrium.
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| Document Type |
article
|
| Language |
English
Russian |
| Publisher Information |
Siberian State Medical University (Tomsk), 2012.
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| Subject Terms | |
