метаболический синдром, эндотелиальная дисфункция, инсулинорезистентность, дислипидемия, артериальная гипертензия, гипергликемия, Agriculture, Science

Background: The role of endothelial dysfunction in patients with metabolic syndrome was investigated. Materials and methods: The study involved 183 patients aged 25 to 65 who which consist of 2 groups. The first group included 60 healthy subjects, in the second group – 123 patients with metabolic syndrome. Diagnosis of metabolic syndrome performed by recommendation ASSC (2008). The exclusion criteria from study was heavy somatic, oncological, hematological and mental diseases. Statistical analysis was performed using the application package StatPlus. Results: the endothelial dysfunction, differences of biochemical analysis was observed in all groups of patient with metabolic syndrome. So differences were established in carbohydrate and lipid metabolism. The features anthropometric indicators were identified at study of Khakas’s and Europeoid’s patients. New data was the amount circulation of endothelial cells in peripheral blood. Conclusion: thus, endothelial dysfunction is important mechanism of pathogenesis. It is forming inter component relationship and features of metabolic syndrome genesis from Khakas‘s and Europeoid’s patients