ABSTRACT: Diet low in milk has been linked to various chronic diseases and cancer. To better understand the global health effect of a diet l
ABSTRACT: Diet low in milk has been linked to various chronic diseases and cancer. To better understand the global health effect of a diet low in milk, this study analyzed the latest data from the Global Burden of Disease study 2021. Our findings revealed that the number of deaths and disability-adjusted life years (DALY) of colon and rectum cancer (CRC) attributable to a diet low in milk increased from 1990 to 2021. The age-standardized mortality rates (ASMR) and age-standardized DALY rates (ASDR) for CRC due to low milk intake declined slightly over this period, with a faster decline observed among females. Predictive analysis shows similar tendency, even higher ASMR and ASDR in CRC associated with a diet low in milk in males than in females by 2050. In contrast, the rate of prostate cancer attributable to a diet low in milk remained relatively stable. Regionally, southern Latin America exhibited the highest ASMR and ASDR for CRC associated with a diet low in milk in 2021, whereas western sub-Saharan Africa had the most notable changes in these rates for prostate cancer. The largest decrease in ASMR and ASDR of CRC due to a diet low in milk was observed in the high socio-demographic index (SDI) region. In addition, the low SDI region exhibited the highest change rates for prostate cancer attributable to a diet low in milk. In summary, our study provides valuable insights into trends for the global burden of CRC and prostate cancer attributable to a diet low in milk, emphasizing the importance of considering gender, age, regional, and national differences in dietary habits and disease risk when formulating public health policies and dietary recommendations.