Co-agglomeration unique crystal engineering approach; in which the co-precipitated micro-particles of nitramines with other energetic materials co-agglomerated by the slurry method; to modify the energetic properties of attractive nitramines like CL20, HMX, BCHMX, and RDX etc. The interesting properties and structural modifications in newly prepared co-agglomerated crystals (CACs) interesting one are discussed here. There are notable variations in the crystal morphologies and packing of crystals, including key properties like relatively high density, melting point, impact sensitivity, and detonation properties. These CACs are in the overwhelming and majority showing properties like co-crystals. Apart from these aspects, co-agglomeration provides a huge opportunity to tune the key properties and performance of existing energetic materials and is easy to scale-up for the industrial level. These preliminary results also suggest that chemical engineering factors are involved in the preparation of CACs and have tremendous improvements than the conventional crystallization. With technological optimization this method can be employable industrial scale production.