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Academic Journal
Prognosis and Chemotherapeutic Efficacy in Extrahepatic Cholangiocarcinoma With Lung Metastases
Chao Zhang, Shun Tu, Yanting Liao, Yaqiang Shu, Muyu Fu, Jiayue Li, Xiaohua Lei
Cancer Reports, Vol 8, Iss 5, Pp n/a-n/a (2025)
Sparad:
| Titel | Prognosis and Chemotherapeutic Efficacy in Extrahepatic Cholangiocarcinoma With Lung Metastases |
|---|---|
| Författarna | Chao Zhang, Shun Tu, Yanting Liao, Yaqiang Shu, Muyu Fu, Jiayue Li, Xiaohua Lei |
| Utgivningsår |
2025
|
| Källa |
Cancer Reports, Vol 8, Iss 5, Pp n/a-n/a (2025)
|
| Beskrivning |
ABSTRACT Objective Studies on lung metastases from extrahepatic cholangiocarcinoma (ECC) are rare. This study aims to fill this gap by analyzing the influencing factors, prognosis, and chemotherapeutic efficacy of ECC lung metastases, and to provide insights for optimizing medical care for patients with ECC lung metastases. Methods We retrieved data from the Surveillance, Epidemiology and End Results (SEER) database for patients with metastatic ECC (stage M1) from 2018 to 2021. The study analyzed these characteristics using descriptive statistics. To calculate Hazard Ratios (HR), multivariate COX regression analyses were performed. Overall survival (OS) was estimated using the Kaplan–Meier method, and the survival of patients between groups was compared using the log‐rank test. Results A total of 762 people participated in the study, 50.4% of whom were men. At the time of diagnosis, 17.8% of patients had pulmonary metastases. 52.5% received chemotherapy. Multivariate COX analysis identified lung metastases as a significant risk factor for death from metastatic ECC (HR 1.64, CI 1.32–2.03, p
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| Dokumenttyp |
article
|
| Språk |
English
|
| Information om utgivare |
Wiley, 2025.
|
| Ämnestermer | |
