Objective: To assess heterogeneity in marijuana use among adolescent Asian American and Pacific Islander (AAPI) subgroups. Methods: AAPI high school students (n = 31,071) participating in the 2019–2020 California Student Tobacco Survey were categorized by race/ethnicity and examined for ever and current (past-30-day) marijuana use. Descriptive statistics were used to describe marijuana use and harm perceptions by subgroups. Multiple logistic regression was used to compare subgroups on marijuana use with other demographics as covariates. Results: Current marijuana use rates by ethnic subgroups were: Chinese 4.2 %, Koreans 4.9 %, Indians 5.2 %, Vietnamese 6.0 %, Hmong 6.4 %, Pakistanis 6.6 %, Japanese 9.4 %, Filipinos 9.6 %, Cambodians 17.9 %, other monoethnic Asians 10.5 %, and Pacific Islanders 22.3 %. Current use rates for monoethnic, multiethnic, and multiracial AAPIs were 7.3 %, 9.1 %, and 18.5 %, respectively, with multiracial AAPIs using at a higher rate than monoethnic and multiethnic AAPIs (both p's