Aim: Evaluation of stresses induced on over-denture abutments endodonticaly treated with two different obturation techniques. Materials and methods: eight mandibular permanent canines were inserted in four pesudo-realistic models. In each model two canines were placed in it. One canine was treated with lateral obturation technique and the other canine with vertical obturation technique. Four over-denture prostheses were fabricated on the four models. Then strain gauges were attached on the coronal one third of the root buccally and lingually for all eight canines. A metal rod was placed occlusally on the premolar –molar area, and a 50 N load was applied on the middle of the rod using the universal testing machine. Readings were collected. Results: from the collected data the lateral obturation showed 85.25±104.901 µε and the vertical obturation showed 4.875±3.555 µε with significance difference of P