hypothalamic-pituitary dysfunction, transcranial magnetic therapy, menstrual irregularities, neurogenic urinary bladder dysfunction, constitutional delay of growth and puberty, Medicine (General), R5-920

Aspects of reactivation and remediation of impaired functions of the brain and of the inner organs regulatory systems are crucial to medical science. The study presents the technique of transcranial magnetic therapy (TMT) with extremely low frequency alternating magnetic field employed for balanced activation of central nervous system function. This study was aimed to assess the effectiveness of TMT in diseases caused by hypothalamic–pituitary dysfunction. Material and Methods ― 90 children aged 10-16 years with different diseases but with similar pathogenic patterns were enrolled in the study. Group 1 included 30 adolescent girls with menstrual irregularities. Group 2 included 30 children with nocturnal enuresis. Group 3 included 30 teenage boys with constitutional delay of growth and puberty. Medical histories were studied, clinical and laboratory evaluation was carried out. TMT stimulation was performed using the device “AMO-ATOS” (TRIMA LLC, Saratov, Russia). Results ― Children in all the groups had high incidence of antenatal and perinatal pathologies recorded in their medical histories. Analysis of electroencephalograms (EEG) showed the prevalence of disorganized and flat EEG patterns – 70% in all the children. Sympathicotonia being the symptom of autonomic nervous system dysfunction, prevailed in 60-80% of the children. The children in the three groups had hormonal imbalance. The treatment with TMT resulted in considerable improvement in hormonal balance and laboratory findings. Conclusion ― ТМТ stimulation is effective in remediation of impaired functions of the brain and treatment of the diseases caused by hypothalamic–pituitary dysfunction.